Results 91 to 100 of about 40,308 (282)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2013 The level and completeness of spinal cord injury (SCI) above the first lumbar vertebra determine the degree of multi-system impairments including altered respiratory function and decreased capacity to maintain upright posture and seated postural ...
Kuipers, Meredith J.
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Understanding the Persistence of Inflation in Argentina: From Peron to Milei [PDF]
Financial and Economic ReviewArgentina’s repeated failures to achieve lasting inflation control reflect not merely technical mismanagement, but also the country’s deep-seated political and institutional rigidities.
Mario I Blejer
doaj +1 more source
Characteristics of the balance of rowers trunk in the seated position
, 2006 The objective of this study was to evaluate the characteristics of the balance of rowers trunk, in the seated position. The research is characterized as descriptive exploratory, having 30 rowers of the male sex with age between 15 and 28 years old as ...
Macedo, Fabiane de Oliveira
core
, 2018 Background and Objective: The aim of this study was to show the effects of an 8-week Neurodevelopmental Treatment based posture and balance training on postural control and balance in diparetic and hemiparetic Cerebral Palsied children (CPC).
Tekin, Fatih +3 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Balance and mobility functional tests in the prediction and prevention of risks of falls in elderly
, 2015 INTRODUCTION: The prevention of falls in the elderly is a challenge for health professionals. One of the most important aspects for such prevention is early detection of risk factors for falls.
Adriana Leite Curcio Cruz (12818166) +3 more
core +1 more source
Environmental impact of intensive farming in sloping areas
MATEC Web of Conferences, 2018 The increased demand for food causes intensive farming with high yield production and large water consumption to extend significantly. Depending on soil properties, seasonal rainfall, surface drainage and water resources, hence the consumption ...
Bosco Giovanni, Simeoni Lucia
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source