Results 71 to 80 of about 40,308 (282)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Balance maintenance in normal seated reach.

, 2004
Seated reach capability is limited by the strength, range of motion, and balance capabilities of the individual. In forward reaches people are able to maintain balance by generating forces and torques at their hips, supporting themselves over their legs.
Parkinson, Matthew Bryce
core  

Association between seated postural control and gait speed in knee osteoarthritis

, 2013
The purpose of this study was to evaluate, in patients with knee osteoarthritis, whether seated postural control is a multivariate predictor of gait speed, after adjusting for the effects of conventional knee impairments.
Liang, Z, Ong, P H, Clark, Ross, Pua, Y H, Lo, N N, Bryant, A L   +5 more
core   +1 more source

Acute Effects of Physical, Cognitive, and Combined Exercise on Executive Functions During Postural Challenge in Older Adults with Mild Cognitive Impairment

Applied Sciences
Mild cognitive impairment (MCI) compromises executive control, yet brief exercise may yield acute cognitive benefits. We tested whether a single ~10 min bout of physical, cognitive, or combined physical-cognitive exercise modulates Stroop performance in ...
Eirini Giatagani, Konstantina Dipla, Dimitrios A. Patikas, Lida Mademli   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Modelling of heat and mass transfer processes in neonatology

, 2008
This paper reviews some of our recent applications of Computational Fluid Dynamics (CFD) to model heat and mass transfer problems in neonatology and investigates the major heat and mass transfer mechanisms taking place in medical devices such as ...
Ginalski, MK, Wrobel, LC, Nowak, AJ
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The effects of attention capacity on dynamic balance control following concussion

Journal of NeuroEngineering and Rehabilitation, 2011
The purpose of this study was to examine how individuals modulate attention in a gait/cognition dual task during a 4-week period following a concussion.
Chou Li-Shan, van Donkelaar Paul, Catena Robert D   +2 more
doaj   +1 more source