Results 51 to 60 of about 269,580 (290)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Exergame design for elderly users: the case study of SilverBalance [PDF]

, 2010
In this paper, we discuss chances and challenges of game design for an elderly audience with a focus on the development of safe and usable exertion games for frail senior citizens.
Gerling, Kathrin, Masuch, Maic, Schild, Jonas   +2 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Validity and reliability of center of pressure measures to quantify trunk control ability in individuals after stroke in subacute phase during unstable sitting test

Heliyon, 2022
Objective: The objective of this study was to assess, for individuals with hemiparesis after a stroke in subacute phase, the validity and reliability of center of pressure (CoP) parameters measured during sitting balance on an unstable support. Materials
Anne-Violette Bruyneel, Serge Mesure, Aline Reinmann, Caroline Sordet, Pablo Venturelli, Irmgard Feldmann, Emmanuel Guyen   +6 more
doaj   +1 more source

Biomechanical comparison of shorts with different pads: An Insight into the Perineum Protection Issue [PDF]

, 2015
An intensive use of the bicycle may increase the risk of erectile dysfunction and the compression of the perineal area has been showed to be a major mechanism leading to sexual alterations compromising the quality of life.
Marcolin, Giuseppe, Panizzolo, Fausto A., Paoli, Antonio, Petrone, Nicola, Reggiani, Carlo   +4 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Smartphone Assessment of the Sitting Heel-Rise Test

Sensors
The study presents a new approach for assessing plantarflexor muscles’ function using a smartphone. The test involves performing repeated heel raises for 60 s while seated.
Gustavo O. Hoffmann, Edilson Borba, Eduardo H. Casarotto, Gisele Francine Devetak, Ramzi Jaber, John G. Buckley, André L. F. Rodacki   +6 more
doaj   +1 more source

ISSLS PRIZE IN BIOENGINEERING SCIENCE 2019: biomechanical changes in dynamic sagittal balance and lower limb compensatory strategies following realignment surgery in adult spinal deformity patients. [PDF]

, 2019
Study designA longitudinal cohort study.ObjectiveTo define a set of objective biomechanical metrics that are representative of adult spinal deformity (ASD) post-surgical outcomes and that may forecast post-surgical mechanical complications.
Bailey, Jeannie F, Berven, Sigurd H, Burch, Shane, Chu, Leslie, Curran, Patrick, Deviren, Vedat, Lotz, Jeffrey C, Matthew, Robert P, Seko, Sarah   +8 more
core  

Balance Control of Semiactive Seat Suspension with Elimination of Dynamic Jerk

Procedia Engineering, 2014
AbstractThe paper presents modification of the conventional balance control of semi-active suspension systems aiming at the elimination of the damping force and consequently sprung mass acceleration discontinuities (dynamic jerk). An analysis of the relationship between the relative displacement of the sprung mass and the relative velocity between the ...
Segla, Stefan, Orecny, Martin
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source