Results 41 to 50 of about 40,308 (282)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Competitive balance in complex professional sports leagues [PDF]

open access: yes, 2008
Competitive balance is seen as crucial to the viability of professional sports leagues, and it has been a central concern of sports economists, industry practitioners and fans. But the concept is complex and ill-defined. The theoretical approach in this
Kringstad, Morten
core  

Incorporation of a dual-task cognitive exercise during unsupported seated balance in collegiate para athletes

open access: yesFrontiers in Cognition
IntroductionBalance remains a critical element in the evaluation and management of sports injury, with recent recommendations to integrate dual-task cognitive exercises into balancing to further challenge the body's vestibular and somatosensory systems ...
Ryan N. Moran, Alexandra C. Curry
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A combined study of heat and mass transfer in an infant incubator with an overhead screen

open access: yes, 2007
The main objective of this study is to investigate the major physical processes taking place inside an infant incubator, before and after modifications have been made to its interior chamber.
Ginalski, MK   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Wheelchair Tai Chi Ball Exercise for Improving Neuromuscular Functions of Older Adults With Disability

open access: yesFrontiers in Aging Neuroscience, 2022
The purposes of this perspective article were to summarize Wheelchair or Seated Tai Chi studies related to neuromuscular functions of older adults with disability; to describe the development of Wheelchair Tai Chi Ball (WTCB) exercise — a concept to ...
Ting Liao   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Balance Control of Semiactive Seat Suspension with Elimination of Dynamic Jerk

open access: yesProcedia Engineering, 2014
AbstractThe paper presents modification of the conventional balance control of semi-active suspension systems aiming at the elimination of the damping force and consequently sprung mass acceleration discontinuities (dynamic jerk). An analysis of the relationship between the relative displacement of the sprung mass and the relative velocity between the ...
Segla, Stefan, Orecny, Martin
openaire   +1 more source

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