Results 61 to 70 of about 40,308 (282)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The Effectiveness Of A Strength Training Program On Extremity Strength, Flexibility, And Balance Of Elderly Women

, 1998
This quasi-experimental study, partially replicating that of Nelson and Wernick (1997), compares balance, flexibility, and extremity strength before and after an 8-week weight-bearing exercise class. Six women, aged 69 to 85, used 1-5 pound wrist weights
Murphy, Patricia L.
core   +1 more source

Robotic balance assessment in community-dwelling older people with different grades of impairment of physical performance [PDF]

, 2020
Background: Impaired physical performance is common in older adults and has been identified as a major risk factor for falls. To date, there are no conclusive data on the impairment of balance parameters in older subjects with different levels of ...
Puntoni, Matteo, Vallone, Francesco, De Michieli, Lorenzo, De Luca, Alice, Giorgeschi, Angela, Saglia, Jody, Squeri, Valentina, Parodi, Sara, Sanfilippo, Carlo, Senesi, Barbara, Cella, Alberto, Pilotto, Alberto, Garofalo, Valentina, Zigoura, Ekaterini   +13 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Robot-Based Assessment of Sitting Balance: Muscular Responses to Self- and Externally-Controlled Perturbations in Seated Position

IEEE Access
In the field of rehabilitation, traditional methods for assessing and training core stability and trunk control involve exercises targeting breathing, muscle strengthening, and both static and dynamic balance.
G. Marchesi, V. Squeri, A. Bellitto, G. Pinna, C. Pierella, A. Canessa, A. de Luca, M. Casadio   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

THE RELATIONSHIP BETWEEN HEART RATE VARIABILITY AND ATHLETIC PERFORMANCE IN BASKETBALL PLAYERS

Türk Fizyoterapi ve Rehabilitasyon Dergisi
Purpose: For basketball players, improving athletic performance is one of the main keys to success and the autonomic nervous system can also affect athletic performance. Heart rate variability (HRV) can be associated with sportive performance as a marker
Burak KARAHAN, Hilal ASLAN, Emre UYSAL, Rabia Tuğba TEKİN   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Validation of seated postural control measures in non-ambulatory persons with Multiple Sclerosis [PDF]

, 2015
Poor seated postural control negatively impacts the performance of daily activities in non-ambulatory persons with Multiple Sclerosis (PwMS) and may be a potential target of rehabilitation.
Ousley, Cherita M.
core