Results 101 to 110 of about 40,308 (282)
[Women at Life of Balance luncheon]
A photograph of women at the League of Professional Women Life of Balance luncheon, held in the Silver Eagle Suites.
University of North Texas. Multicultural Center.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Effect of equine-assisted therapy on the postural balance of the elderly [PDF]
OBJECTIVE: To determine whether equine-assisted therapy (hippotherapy) produces alterations in the balance of the elderly. METHODS: The sample included 17 older adults who were divided into experimental (7 subjects) and control (10 subjects) groups ...
Nélida A. Silva +9 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
[Woman speaking at Life of Balance luncheon]
A photograph of a woman speaking at the League of Professional Women Life of Balance luncheon, held in the Silver Eagle Suites. She is standing behind a wooden podium with the UNT logo on the front of it and there is a projection screen set up beside her.
University of North Texas. Multicultural Center.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Assessing balance through the use of a low-cost head-mounted display in older adults: a pilot study
Santiago J Saldana,1 Anthony P Marsh,2 W Jack Rejeski,2 Jack K Haberl,2 Peggy Wu,3 Scott Rosenthal,4 Edward H Ip1 1Department of Biostatistical Sciences, Wake Forest School of Medicine, 2Department of Health and Exercise Science, Wake Forest University,
Ip EH +6 more
core
Evaluation of the trunk biomechanical responses to seated whole-body vibration exposure [PDF]
Risk factors for low-back disorders -- Whole-body vibration -- Spinal stability -- Assessment of the neural control subsystem -- Assessment of the passive subsystem -- Assement of active subsystem -- Reliability of centre of pressure measures of postural
Santos, Brenda
core

