Results 191 to 200 of about 14,450 (260)

Complications Following Nictitating Membrane Resection in Horses: 92 Eyes (2015–2024)

open access: yesVeterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective The goal of this retrospective study is to evaluate the complications following nictitating membrane resection in horses with the aim of providing valuable information on the risks of this surgical procedure. Animals 83 horses (92 eyes). Procedures Medical records for 83 horses that underwent nictitating membrane resection in 92 eyes
Tiantian Wu   +2 more
wiley   +1 more source

Single-Cell RNA Profiling of Ocular Adnexal Sebaceous Carcinoma Reveals a Complex Tumor Microenvironment and Identifies New Biomarkers. [PDF]

open access: yesAm J Ophthalmol
Zhang MG   +9 more
europepmc   +1 more source

DNA–Peptide Crosslinks Placed at Codon 249 of the p53 Tumor Suppressor Gene Induce G to A Transitions in Human Cells

open access: yesChemBioChem, Volume 27, Issue 16, 27 August 2026.
DNA‐peptide cross‐links (DpCs) are ubiquitous DNA lesions that form when cellular proteins become covalently trapped on DNA strands and are processed by proteases. DpCs are hypothesized to play a role in antitumor activity of chemotherapeutic drugs and to contribute to aging.
Priscilla Yawson   +4 more
wiley   +1 more source

Synthesis and Biological Activity of 2,6‐Disubstituted and 2,6,9‐Trisubstituted 7‐Deazapurine Nucleobases

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Four series of 20 (het)aryl substituted 7‐deazapurine nucleobases were synthesized. Several potent antagonists of all four subtypes of adenosine receptors were identified by functional assay. High‐throughput screening of the IMTM compound library for modulatory activity on adenosine receptors (ARs) identified two deazapurine hits based on 2,6‐diaryl‐7 ...
Ugnė Šinkevičiūtė   +9 more
wiley   +1 more source

Valorization of fruit pits from Prunus laurocerasus and Prunus cerasifera as agro‐food byproducts: Bioactive properties and safety assessment for potential food additive applications

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 6002-6014, 15 August 2026.
Abstract BACKGROUND Food additives are widely used to extend the shelf life of foods and maintain their quality. In this study, the potential of Prunus laurocerasus and Prunus cerasifera fruit pits (endocarp and seed) as food additives was investigated in terms of cytotoxicity, antigenotoxicity, antioxidant activity, enzymatic anti‐browning, and urease
Zühal Bayrakçeken Güven   +4 more
wiley   +1 more source

Exploring the Chemical Space Around Protoflavonoids: Synthesis and Antitumor Activity of Protochalcones

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Natural and synthetic protoflavonoids offer potent anticancer properties, but their chemical space remains largely unexplored. This study details the synthesis of eleven p‐hydroxydienone derivatives from chalcone precursors. We evaluated their antiproliferative effects across four human gynecological cancer cell lines.
Tímea Gonda   +7 more
wiley   +1 more source

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