Results 151 to 160 of about 37,948 (349)

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

open access: yesAdvanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen   +14 more
wiley   +1 more source

Role of Fine Needle Aspiration Cytology in Salivary Gland Pathology and its Histopathological Correlation: A Two Year Prospective Study in Western India. [PDF]

open access: yes, 2012
Background and objectives: Salivary gland lesions account for 2-6.5% of all the neoplasms of the head and neck. Fine needle aspiration cytology (FNAC) is being increasingly used in the diagnosis of salivary gland lesions.
Agravat, AH   +3 more
core   +1 more source

SEBACEOUS GLAND CARCINOMA

open access: yesAnnals of Surgery, 1942
A, Beach, A O, Severance
openaire   +3 more sources

Reccurent Sebaceous Gland Carcinoma of the Eyelid with Metastasis to the Parotid Gland and the Regional Lymph Nodes: Case Report and Review of the Literature [PDF]

open access: hybrid, 2019
Margarita Vafeiadou   +4 more
openalex   +1 more source

Detection of Epstein-Barr Virus in 130 Cases of Eyelid Sebaceous Gland Carcinoma Using In Situ Hybridization [PDF]

open access: gold, 2020
Huanhuan Gao   +5 more
openalex   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

Curious Case of Swelling over the Back: A Case Report of Sebaceous Cell Carcinoma in a Patient of Airborne Contact Dermatitis

open access: yesClinical Dermatology Review
Sebaceous carcinoma is a rare variety of malignant tumor involving sebaceous glands. Compared to its ocular counterpart, the extraocular variant is even more rare, accounting for only one-fourth of all cases.
Sonia Jain   +2 more
doaj   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen   +7 more
wiley   +1 more source

Brief Note Dorsal and Anal Glands in the Eastern Chipmunk, Tamias Striatus [PDF]

open access: yes, 1979
Author Institution: Department of Zoology and Microbiology, Ohio ...
Allen, B. L.   +2 more
core  

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

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