Results 61 to 70 of about 4,536 (192)

Darier disease: Current insights and challenges in pathogenesis and management

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 942-951, May 2025.
Darier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Monika Ettinger, Susanne Kimeswenger, Isabella Deli, Judith Traxler, Sabine Altrichter, Petar Noack, Jakob D. Wikstrom, Emmanuella Guenova, Wolfram Hoetzenecker   +8 more
wiley   +1 more source

Bowenoid transformation in seborrheic keratosis: A retrospective analysis of 429 patients

Journal of Research in Medical Sciences, 2012
Background: Seborrheic keratosis is a common, benign skin tumor. Numerous reports have shown its possibility of malignant transformation. This study was designed to demonstrate the occurrence of concomitant seborrheic keratosis and skin cancers ...
Parvin Rajabi, Neda Adibi, Pardis Nematollahi, Mitra Heidarpour, Mehdi Eftekhari, Amir Hossein Siadat   +5 more
doaj  

No evidence of human papillomaviruses in non-genital seborrheic keratosis

Indian Journal of Dermatology, 2013
Background: Seborrheic keratosis (SK) is a benign epidermal tumor of unknown etiology. Because of its wart-like morphology, Human papillomaviruses (HPVs) have been suggested as a possible causative agent.
Naser Tayyebi Meibodi, Yalda Nahidi, Zahra Meshkat, Habibollah Esmaili, Masoumeh Gharib, Aida Gholoobi   +5 more
doaj   +1 more source

Exploring the Properties and Application Potential of β‐Glucan in Skin Care

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
β‐glucan is a natural polysaccharide with significant immunomodulatory, antioxidant, anti‐inflammatory, and moisturizing effects, making it a promising ingredient for skin care applications. This review systematically explores its properties, biological mechanisms, and clinical applications, offering theoretical support and guidance for future research
Xiaoyue Feng, Jianli Shang, Yuhui Wang, Yong Chen, Youting Liu   +4 more
wiley   +1 more source

Estimation of the state of proliferative activity and expression of the oncomarker p53 in samples of actinic keratosis.

Морфологія, 2017
Background. Actinic keratosis is a precancerous condition of the skin, which most often occurs in the open areas of the skin (primarily, the head, neck and extremities) after prolonged or intense natural or artificial irradiation by ultraviolet rays in ...
V. S. Hlushok, T. V. Sviatenko, I. S. Shponka, O. V. Poslavska   +3 more
doaj   +1 more source

Mosaic Darier's Disease: A Case of Unilateral Localized Type I Segmental Darier's Disease

Clinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT Darier's disease (DD), also known as Darier‐White disease, is a rare autosomal dominant genodermatosis resulting from mutations in the ATP2A2 gene. It commonly manifests as keratotic papules or plaques in seborrheic areas and is often triggered by heat, sweating, and trauma. A rare mosaic variant, segmental Darier's disease, occurs due to post‐
Lina Al‐Soufi, Aya Marashli, Hamza Warda, Zuheir Al‐Shehabi   +3 more
wiley   +1 more source

Verruca plana mimicking seborrheic keratosis in the elderly: A case report

IDCases, 2019
Verruca plana is a common viral infection in childhood and early adulthood caused by the human papillomavirus. The clinical presentation can mimic that of benign epithelial neoplasms, particularly seborrheic keratosis, which is common in the elderly.
Thanadon Eksomtramage, Kumpol Aiempanakit   +1 more
doaj  

Application of Medical Images for Melanoma Detection Using a Multi‐Architecture Convolutional Neural Network From a Deep Learning Approach

Engineering Reports, Volume 7, Issue 3, March 2025.
Deep‐learning techniques were applied in this study. EfficientNetB3, MobileNetV2, and InceptionV3 were employed to assess their effectiveness in detecting melanoma. Among these architectures, EfficientNetB3 emerged as the standout performer, achieving an exceptional accuracy rate of 90.7% and an impressive area under the curve (AUC) score of 97%.
Justice Williams Asare, Emmanuel Akwah Kyei, Seth Alornyo, Emmanuel Freeman, Martin Mabeifam Ujakpa, William Leslie Brown‐Acquaye, Alfred Coleman, Forgor Lempogo   +7 more
wiley   +1 more source

A Review of Melanoma Subtypes: Genetic and Treatment Considerations

Journal of Surgical Oncology, Volume 131, Issue 3, Page 356-364, March 2025.
ABSTRACT Melanoma affects over one million people in the United States. This review explores genetic mutations and markers of all seven subtypes. Current treatment options and prognosis of each subtype are also discussed. For lentigo maligna, spitzoid, and nodular subtypes, BRAF was the most common mutation reported. For superficial spreading, TP53 was
Christina Druskovich, Jesse Kelley, Jason Aubrey, Leah Palladino, G. Paul Wright   +4 more
wiley   +1 more source

Prevalência das lesôes cutâneas em Freixo de Espada à Cinta.

Acta Médica Portuguesa, 2000
Incidence or prevalence studies on cutaneous lesions in general populations are not available. The community observed by the authors (Freixo de Espada à Cinta, North-Eastern Portugal) is relatively closed. A pre-tested questionnaire for socio-demographic
A Massa, R Alves, J Amado, E Matos, M Sanches, M Selores, C Santos, V Costa, G Velho, M Oliveira, E Ferreira, M Taveira, N S Silva, E Granado, A Lemos, J M Calheiros   +15 more
doaj   +1 more source