Results 11 to 20 of about 96,483 (275)
SecA inhibitors as potential antimicrobial agents: differential actions on SecA-only and SecA-SecYEG protein-conducting channels [PDF]
FEMS Microbiology Letters, 2018 Abstract Sec-dependent protein translocation is an essential process in bacteria. SecA is a key component of the translocation machinery and has multiple domains that interact with various ligands. SecA acts as an ATPase motor to drive the precursor protein/peptide through the SecYEG protein translocation channels.
Jinshan, Jin +7 more
openaire +3 more sources
Structural basis of SecA-mediated protein translocation
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance The vast majority of secretory proteins in bacteria are translocated across the cell membranes through the SecY channel by a highly conserved ATPase, SecA.
Linlin Dong +6 more
semanticscholar +1 more source
Ribosome profiling reveals multiple roles of SecA in cotranslational protein export
Nature Communications, 2022 SecA, an ATPase known to posttranslationally translocate secretory proteins across the bacterial plasma membrane, also binds ribosomes, but the role of SecA’s ribosome interaction has been unclear.
Zikun Zhu, Shuai Wang, S. Shan
semanticscholar +1 more source
Axioms, 2021 There are many sub-tour elimination constraint (SEC) formulations for the traveling salesman problem (TSP). Among the different methods found in articles, usually three apply more than others.
Ramin Bazrafshan +2 more
semanticscholar +1 more source
Cellular dynamics of the SecA ATPase at the single molecule level
Scientific Reports, 2021 In bacteria, the SecA ATPase provides the driving force for protein secretion via the SecYEG translocon. While the dynamic interplay between SecA and SecYEG in translocation is widely appreciated, it is not clear how SecA associates with the translocon ...
Anne-Bart Seinen +3 more
semanticscholar +1 more source
BJS Open, 2020 Patients with metastatic colorectal cancer receiving palliative chemotherapy have a 5‐year survival rate of approximately 10 per cent. Liver transplantation using strict selection criteria in patients with colorectal cancer and unresectable liver‐only ...
T. M. Smedman +5 more
semanticscholar +1 more source
, 2020 The shipping industry has been subjected to significant pressure with the increasingly stringent environmental regulations. All vessels must comply with the IMO 2020 Sulfur cap—using fuel with less than 0.5% of sulfur content in international navigation,
Lixian Fan, Bingmei Gu, M. Luo
semanticscholar +1 more source
The SecA motor generates mechanical force during protein translocation
Nature Communications, 2020 The Sec translocon moves proteins across lipid bilayers in all cells. The Sec channel enables passage of unfolded proteins through the bacterial plasma membrane, driven by the cytosolic ATPase SecA.
Riti Gupta +2 more
semanticscholar +1 more source
EMBO Reports, 2020 Bacterial secretory proteins are translocated post‐translationally by the SecA ATPase through the protein‐conducting SecY channel in the plasma membrane. During the ATP hydrolysis cycle, SecA undergoes large conformational changes of its two‐helix finger
Marco A Catipovic, T. Rapoport
semanticscholar +1 more source
Crescimento e produção do gergelim em diferentes níveis de solução organomineral
Revista Verde de Agroecologia e Desenvolvimento Sustentável, 2016 O Gergelim (Sesamum indicum L.), espécie pertencente à família Pedaliaceae, é uma das oleaginosas, mais antigas utilizadas pela humanidade com potencial para diversos fins industriais.
Emerson Lúcio Gomes Silva +4 more
doaj +1 more source