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SecA inhibitors as potential antimicrobial agents: differential actions on SecA-only and SecA-SecYEG protein-conducting channels [PDF]
FEMS Microbiology Letters, 2018 Abstract Sec-dependent protein translocation is an essential process in bacteria. SecA is a key component of the translocation machinery and has multiple domains that interact with various ligands. SecA acts as an ATPase motor to drive the precursor protein/peptide through the SecYEG protein translocation channels.
Sen-Fang Sui, Binghe Wang, Phang C Tai
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Proceedings of the 2005 international conference on Compilers, architectures and synthesis for embedded systems, 2005
In this work, we propose and investigate the idea of enhancing a System-on-Chip (SoC) communication architecture (the fabric that integrates system components and carries the communication traffic between them) to facilitate higher security. We observe that a wide range of common security attacks are manifested as abnormalities in the system-level ...
Joel Coburn +3 more
openaire +2 more sources
In this work, we propose and investigate the idea of enhancing a System-on-Chip (SoC) communication architecture (the fabric that integrates system components and carries the communication traffic between them) to facilitate higher security. We observe that a wide range of common security attacks are manifested as abnormalities in the system-level ...
Joel Coburn +3 more
openaire +2 more sources
Journal of Molecular Biology, 1997
The protein translocation ATPase of Escherichia coli, SecA protein, auto-regulates its translation by binding to its translation initiation region in geneX-secA mRNA. To analyze this regulation further the secondary structure of this portion of geneX-secA RNA was investigated utilizing structure-specific nucleases and chemical probing approaches.
R, Salavati, D, Oliver
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The protein translocation ATPase of Escherichia coli, SecA protein, auto-regulates its translation by binding to its translation initiation region in geneX-secA mRNA. To analyze this regulation further the secondary structure of this portion of geneX-secA RNA was investigated utilizing structure-specific nucleases and chemical probing approaches.
R, Salavati, D, Oliver
openaire +2 more sources
1994
Abstract Additional alleles of secA were isolated as suppressors, designated pr/D, of signal peptide defects in maltose-binding protein2and as mutants, designated azi, which confer resistance of growth to sodium azide, an inhibitor of SecA ATPase activity3.4.
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Abstract Additional alleles of secA were isolated as suppressors, designated pr/D, of signal peptide defects in maltose-binding protein2and as mutants, designated azi, which confer resistance of growth to sodium azide, an inhibitor of SecA ATPase activity3.4.
openaire +1 more source
Revista Paulista de Reumatologia
A saliva é essencial para a homeostasia bucal e as alterações em seu fluxo podem afetar sua composição e função. A hipossalivação é diagnosticada quando o fluxo é inferior a 0,1 mL/min de saliva não estimulada ou 0,7 mL/min de saliva estimulada mecânica ou quimicamente. Para esta avaliação, utilizam-se testes de sialometria estimulados e não estimulado.
Maitê Bertotti +1 more
openaire +1 more source
A saliva é essencial para a homeostasia bucal e as alterações em seu fluxo podem afetar sua composição e função. A hipossalivação é diagnosticada quando o fluxo é inferior a 0,1 mL/min de saliva não estimulada ou 0,7 mL/min de saliva estimulada mecânica ou quimicamente. Para esta avaliação, utilizam-se testes de sialometria estimulados e não estimulado.
Maitê Bertotti +1 more
openaire +1 more source
2013
Security issues are paramount when considering adoption of any cloud technology. This chapter outlines the Secure Cloud Architecture (SeCA) model on the basis of data classifications, which defines a properly secure cloud architecture by testing the cloud environment on eight attributes.
Thijs Baars, Marco Spruit
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Security issues are paramount when considering adoption of any cloud technology. This chapter outlines the Secure Cloud Architecture (SeCA) model on the basis of data classifications, which defines a properly secure cloud architecture by testing the cloud environment on eight attributes.
Thijs Baars, Marco Spruit
openaire +1 more source
2023
[ES] "Entre flores secas" es un libro ilustrado, compuesto de textos e ilustraciones que se acompañan y complementan mutuamente. Los textos son poemas o reflexiones breves, que de una forma u otra tratan la sensibilidad y vivencias de la autora. Las ilustraciones, presentan una combinación entre arte tradicional, buscando experimentar con distintos ...
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[ES] "Entre flores secas" es un libro ilustrado, compuesto de textos e ilustraciones que se acompañan y complementan mutuamente. Los textos son poemas o reflexiones breves, que de una forma u otra tratan la sensibilidad y vivencias de la autora. Las ilustraciones, presentan una combinación entre arte tradicional, buscando experimentar con distintos ...
openaire +1 more source