Results 71 to 80 of about 17,674,138 (204)
Advanced Science, EarlyView.This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu +10 more
wiley +1 more source
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
Advanced Science, EarlyView.This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
A convergence criterion for Secant method with approximate zeros
, 2017 Approximate zeros; Newton method; Secant ...
김선영
core +1 more source
Basal Plane Graphene Coated Zn Powder for High Performance Aqueous Zn Metal Batteries
Advanced Science, EarlyView.A mechanofusion‐driven dry coating forms a hydrophobic graphene shell on Zn powder, stabilizing the electrode‐electrolyte interface. This basal‐plane‐rich protective layer modifies the Zn2+ solvation environment and promotes preferential growth along the (002) plane, suppressing dendrite and parasitic reactions.
Dongju Kim +8 more
wiley +1 more source
Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Advanced Science, EarlyView.Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
, 2008 Cubic polynomial, Newton's MethodSteps of the secant root finding method for a cubic polynomial. The secant method for numerical root finding of the functions f consists of the steps xk+1= xk – f(xk)(xk-xk-1)/(f(xk)
Trott, Michael
core
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
Advanced Science, EarlyView.At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source
Advanced Science, EarlyView.Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho +13 more
wiley +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
Advanced Science, EarlyView.ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
, 2014 Cubic polynomial, Newton's MethodSteps of the secant root finding method for a cubic polynomial. The secant method for numerical root finding of the functions f consists of the steps xk+1= xk – f(xk)(xk-xk-1)/(f(xk)
Trott, Michael
core