Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolites [PDF]
, 2015 Plant ...
Choi, Y.H. +4 more
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Functional Characterization of Monoterpenoid Indole Alkaloid (MIA) Biosynthetic Genes in Catharanthus roseus [PDF]
, 2013 The monoterpenoid indole alkaloids (MIAs) of Madagascar periwinkle (Catharanthus roseus) are known to be among the most important source of natural drugs used in various cancer chemotherapies.
Salim, Vonny
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Exploiting alkaloid biosynthesis in Madagascar periwinkle to obtain natural product derivatives and new biocatalysts [PDF]
, 2010 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2010.Cataloged from PDF version of thesis. Vita.Includes bibliographical references.Plant alkaloid biosynthesis produces many natural products with medicinal value.
Bernhardt, Peter, Ph. D. Massachusetts Institute of Technology
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Discovery, characterization, and rational design of the enzymes involved in monoterpene indole alkaloid biosynthesis in Madagascar periwinkle [PDF]
, 2011 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, February 2011."February 2011." Vita. Cataloged from PDF version of thesis.Includes bibliographical references.The chemical diversity found in plants has served as a major source ...
Giddings, Lesley-Ann
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The biosynthesis of monoterpenoid indole alkaloids from strictosidine [PDF]
, 1979 Nagakura, Naotaka +2 more
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4,21-Dehydrogeissoschizine, an intermediate in heteroyohimbine alkaloid biosynthesis [PDF]
, 1979 Husson, Henri-Phillipe +4 more
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A Catharanthus roseus mutant with trace levels of secologanin and monoterpenoid indole alkaloids does not express BIS1/BIS2 transcription factors and fails to activate iridoid biosynthesis. [PDF]
, 2017 The Madagascar periwinkle (Catharanthus roseus) is the sole source of the monoterpenoid indole alkaloids (MIAs) that result in several essential anti-cancer chemotherapies as well as being an important source for other MIA derived pharmaceutical agents ...
Kidd, Trevor
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Bioinformatic and morphological characterization of Catharanthus roseus mutants [PDF]
, 2019 Catharanthus roseus, a member of the Apocynaceae family, has been studied extensively for its valuable chemotherapeutic monoterpenoid indole alkaloids (MIAs).
Jones, Graham
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Transcriptome assembly reveals putative genes involved in monoterpenoid indole alkaloid biosynthesis in Ochrosia elliptica. [PDF]
Monoterpenoid indole alkaloids (MIAs) are a class of plant-derived secondary metabolites which display valuable pharmacological properties, including the anticancer drug vinblastine from Catharanthus roseus and the antihypertensive reserpine from ...
Edge, Alison
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Substrate analogs to investigate alkaloid biosynthesis in Catharanthus roseus [PDF]
, 2009 Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.Vita.Includes bibliographical references.Terpene indole alkaloids are a class of natural products produced by plants, many of which are used clinically for the treatment of ...
McCoy, Elizabeth Ann, Ph. D. Massachusetts Institute of Technology
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