Enantiopure Indolo[2,3-a]quinolizidines: Synthesis and Evaluation as NMDA Receptor Antagonists [PDF]
, 2016 Enantiopure tryptophanol is easily obtained from the reduction of its parent natural amino acid trypthophan (available from the chiral pool), and can be used as chiral auxiliary/inductor to control the stereochemical course of a diastereoselective ...
Amat Tusón, Mercedes +4 more
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Alkaloid production by a Cinchona officinalis "Ledgeriana" hairy root culture containing constitutive expression constructs of tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus [PDF]
, 1999 Cinchona officinalis ‘Ledgeriana’, former called Cinchona ledgeriana, hairy roots were initiated containing constitutive-expression constructs of cDNAs encoding the enzymes tryptophan decarboxylase (TDC) and strictosidine synthase (STR) from ...
Cardoso, I. Lopes +5 more
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New Phytologist, Volume 242, Issue 3, Page 1156-1171, May 2024.Summary In Catharanthus roseus, monoterpenoid indole alkaloids (MIAs) are produced through the cooperation of four cell types, with final products accumulating in specialized cells known as idioblasts and laticifers. To explore the relationship between cellular differentiation and cell type‐specific MIA metabolism, we analyzed the expression of MIA ...
Mai Uzaki +15 more
wiley +1 more source
Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica [PDF]
, 2017 This dissertation focuses on studying the production of two categories of high-value compounds in bio organisms. The first group is terpenoid indole alkaloids (TIAs) in plant Catharanthus roseus, and the second group is wax esters, one of fatty acid ...
Zhao, Le
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Limitation of mitragynine biosynthesis in mitragyna speciosa (Roxb.) Korth. through tryptamine availability [PDF]
, 2013 Plant ...
Charoonratana, T. +6 more
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Localization of monoterpenoid indole alkaloid (MIA) biosynthesis by in situ hybridization (ISH) [PDF]
, 2013 Monoterpenoid indole alkaloids (MIA) are among the largest and most complex group of nitrogen containing secondary metabolites that are characteristic of the Apocynaceae plant family including the most notable Catharanthus roseus.
Edmunds, Elizabeth
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CHARACTERIZATION OF \u3ci\u3eG10H\u3c/i\u3e PROMOTER AND ISOLATION OF WRKY TRANSCRIPTION FACTORS INVOLVED IN \u3ci\u3eCATHARANTHUS\u3c/i\u3e TERPENOID INDOLE ALKALOID BIOSYNTHESIS PATHWAY [PDF]
, 2011 Catharanthus roseus produces a large array of terpenoid indole alkaloids (TIAs) that are an important source of natural or semi-synthetic anticancer drugs. Biosynthesis of TIAs is tissue-specific and induced by certain phytohormones and fungal elicitors,
Suttpanta, Nitima
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Chemical, biochemical, and molecular characterization of a low vindoline Catharanthus roseus mutant. [PDF]
, 2015 The Madagascar periwinkle (Catharanthus roseus) is the sole source of the anticancer drug vinblastine, which is formed via the coupling of monoterpenoid indole alkaloids (MIAs) catharanthine and vindoline. A mutant line of C.
Edge, Alison
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The Fusarium crown rot pathogen Fusarium pseudograminearum triggers a suite of transcriptional and metabolic changes in bread wheat (Triticum aestivum L.) [PDF]
, 2017 Background and Aims: Fusarium crown rot caused by the fungal pathogen Fusarium pseudograminearum is a disease of wheat and barley, bearing significant economic cost.
Akinsanmi +51 more
core +1 more source
Genome and transcriptome guided gene discovery in plant secondary metabolism [PDF]
, 2016 Plants produce a wide range of complex secondary metabolites that have many applications, for example as pharmaceutical agents. Gene discovery and the elucidation of these unique biosynthetic pathways is challenging since many of the enzymatic ...
Kellner, Franziska
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