Results 11 to 20 of about 73,340 (107)

Total Syntheses of Biosynthetic Intermediates Toward Collective Supply of Biologically Active Alkaloid and Total Synthesis of (—)-Rubenine [PDF]

, 2021
The first enantioselective total syntheses of the biosynthetic intermediates of the monoterpenoid indole alkaloids, (—)- secologanin (1), (—)-5-carboxystrictosidine (2), and (—)-strictosidine (3), were accomplished.
楽満, 憲太, RAKUMITSU, Kenta
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An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine [PDF]

, 2020
The secoiridoid glucoside secologanin is the terpenoid building block in the biosynthesis of terpenoid indole alkaloids. A method for its determination in plant tissues and in cell suspension cultures has been developed.
Jensen, Soren R., Memelink, Johan, Snoeijer, Wim, Heijden, Robert Van Der, Hoge, J. Harry C., Tomaz Jiméréz, Emília M., Contin, Adriana, Pasquali, Giancarlo, Cardoso, M. Inês Lopes, Verpoorte, Robert, Hallard, Didier   +10 more
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Radical Approaches to Alangium and Mitragyna Alkaloids [PDF]

, 2010
The work presented in this thesis has focused on the development of novel and concise syntheses of Alangium and Mitragyna alkaloids, and especial approaches towards (±)-protoemetinol (a), which is a key precursor of a range of Alangium alkaloids such as ...
Palframan, M J
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Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae) [PDF]

, 2013
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability.
Swaleh, S. M., Hassanali, Ahmed, Ndiege, Isaiah O, Brun, R., Dalsgaard, Petur, Ahmed Hassanali, Ndiege, I. O., Malebo, Hamisi M, Monical Cal, Petur Dalsgaard, Maurice O Omolo, Hassanali, A., Wenzler, T., Sequin, U., Hamburger, M., Wenzler, Tanja, Tanja Wenzler, Omolo, M. O., Omolo, Maurice O, Hamisi M Malebo, Dalsgaard, P., Cal, M., Häussinger, Daniel, Daniel Häussinger, Häussinger, D., Hamburger, Matthias, Brun, Reto, Sauda M Swaleh, Malebo, H. M., Séquin, Urs, Isaiah O Ndiege, Reto Brun, Cal, Monical, Swaleh, Sauda M, Urs Séquin, Matthias Hamburger   +35 more
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Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture

, 2009
Natural products have long served as both a source and inspiration for pharmaceuticals. Modifying the structure of a natural product often improves the biological activity of the compound.
Maresh, Justin J., Runguphan, Weerawat, O'Connor, S., O'Connor, Sarah Ellen, Runguphan, W., O'Connor, Sarah E., Maresh, J.   +6 more
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Soil-borne microorganisms and soil-type affect pyrrolizidine alkaloids in Jacobaea vulgaris [PDF]

, 2009
Secondary metabolites like pyrrolizidine alkaloids (PAs) play a crucial part in plant defense. We studied the effects of soil-borne microorganisms and soil-type on pyrrolizidine alkaloids in roots and shoots of Jacobaea vulgaris.
Veen, J.A., van, Klinkhamer, P.G.L., Joosten, L., Mulder, P.P.J.   +3 more
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Pericyclic Reaction Development and Synthetic Studies Aimed at Select Tryptamine Derived Alkaloids [PDF]

, 2018
The initial section of this thesis entails pericyclic reaction development. Chapter 1 details development of a combined Winstein Rearrangement and Tsuji-Trost allylic substitution reaction. Chapter 2 chronicles development of a domino dibromocyclopropane
Kim, Simon J
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Isolation and X-ray crystal structure of tetrahydroisoquinoline alkaloids from Calycotome villosa Subsp. intermedias [PDF]

, 2004
Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia.
Bolte, Michael, El Alami, Rachid, El Bali, Brahim, Messouri, Ibtissam, Bouktaib, Mohamed, Rachid El Alami, Brahim El Bali, Michael Bolte, El Antri, Ali, Mohamed Bouktaib, Ibtissam Messouri, Lachkar, Mohammed, Mohammed Lachkar, Ali El Antri   +13 more
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Bisindole alkaloids

, 2006
This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed ...
Toh-Seok Kam, Choo, Yeun Mun, Kam, Toh Seok, Yeun-Mun Choo   +3 more
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Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding [PDF]

, 2020
A transgenic cell suspension culture of Nicotiana tabacum L. ‘Petit Havana’ SR1 was established expressing tryptophan decarboxylase and strictosidine synthase cDNA clones from Catharanthus roseus (L.) G.
Hallard, D., Cardoso, M.I. Lopes, Verpoorte, R., Pasquali, G., Hoge, J.H.C., Memelink, J., Heijden, R Van Der   +6 more
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