Results 191 to 200 of about 37,162 (308)

Response to comment on the recently published article "An update on recently approved long-acting injectable second-generation antipsychotics: Knowns and unknowns regarding their use". [PDF]

Ment Health Clin, 2023
VandenBerg AM.
europepmc   +1 more source

Editorial: Second-generation antipsychotics — a panacea?

South African Journal of Psychiatry, 2016
No ...
openaire   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

Patient Life Engagement and Metabolic Profile Improve After Switching from First-/Second-Generation Antipsychotics to Brexpiprazole: A Real-World Study in Patients with Schizophrenia. [PDF]

J Pers Med
Di Nicola M, Pepe M, Milintenda M, Massetti M, Moccia L, Panaccione I, Sani G.   +6 more
europepmc   +1 more source

Differential Neuronal Development in iPSC‐Derived Neural Stem Cells From Monozygotic Twin Cases With Treatment‐Resistant Schizophrenia and Discordant Responses to Clozapine

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We investigated early neuronal development using iPSCs from twins with treatment‐resistant schizophrenia discordant for clozapine response. The non‐responder exhibited more pronounced impairment in differentiation than the responder. Transcriptomic analysis revealed distinct developmental gene expression profiles, suggesting that early ...
Shotaro Kawano, Sayaka Katayama, Masaya Ogawa, Rei Endo, Naoto Ikeda, Yuuri Ikeuchi, Tomoki Mita, Hikari Takei, Nanaka Gotoda‐Nishimura, Daiki Miura, Hotaka Fukushima, Hitoshi Hashimoto, Ryota Hashimoto, Takanobu Nakazawa   +13 more
wiley   +1 more source

Non-adherence and predictors in patients with schizophrenia on second generation antipsychotics at Amanuel Mental Specialized Hospital, Ethiopia. [PDF]

PLoS One
Beyene MG, Teferra S, Fenta TG.
europepmc   +1 more source

Association Between Psychiatrists' Subjective Clinical Behavior Scores and Objective Quality Indicators Based on Discharge Prescriptions: A Nationwide Multicenter Study Based on the EGUIDE Project

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Association between quality indicators and clinical behaviors related to the guidelines for schizophrenia. ABSTRACT Aim Psychiatrists often perceive their clinical practices as guideline‐concordant; however, discrepancies frequently exist between perceived and actual prescribing behaviors.
Kazuhiko Yamamuro, Naomi Hasegawa, Yusuke Arai, Hikaru Hori, Hiroyuki Muraoka, Toru Horinouchi, Naoki Hashimoto, Shinichiro Ochi, Takashi Tsuboi, Hirotaka Yamagata, Junya Matsumoto, Satsuki Ito, Toshiaki Onitsuka, Kazutaka Ohi, Hisashi Yamada, Jun‐ichi Iga, Ken Inada, Koichiro Watanabe, Norio Yasui‐Furukori, Ryota Hashimoto   +19 more
wiley   +1 more source

Low to moderate-dose off-label use of second-generation antipsychotics seems to be safe in the light of cardiac adverse effects in child psychiatric patients. [PDF]

Eur J Pediatr
Kakko K, Salmelin R, Puura K, Poutanen T.   +3 more
europepmc   +1 more source

Comorbid Schizophrenia and Psychotic Symptoms in Patients With Bipolar Disorder: A Meta‐Analysis of the Global Literature

Bipolar Disorders, Volume 28, Issue 3, May 2026.
ABSTRACT Background The boundary between bipolar disorder and schizophrenia has long been blurred by the shared psychopathology, genetic risk, and social factors. This study aims to examine the prevalence of psychosis and psychotic symptoms in bipolar patients.
Wen Shao, Kangning Shao, Richard P. Bentall   +2 more
wiley   +1 more source

Genome Wide Association Study (GWAS) Identifies Novel Genetic Loci for Second-Generation Antipsychotics (SGA)-Induced Metabolic Syndrome (MetS). [PDF]

Clin Transl Sci
El Rouby N, Owusu-Obeng A, Preuss MH, Lee S, Shi M, Nadukuru R, Van Driest SL, Mosley JD, DelBello M.   +8 more
europepmc   +1 more source