Results 211 to 220 of about 37,162 (308)

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Cerebral Computed Tomographic Findings in Schizophrenia: Relationship to Second-Generation Antipsychotics and Hyperprolactinemia. [PDF]

Healthcare (Basel)
Petric PS, Ifteni P, Popa AV, Teodorescu A.   +3 more
europepmc   +1 more source

Trends and Disparities in Atrial Fibrillation‐Related Mortality Among Older Adults With Parkinson's Disease in the United States, 2000–2023

Journal of Arrhythmia, Volume 42, Issue 2, April 2026.
Central Illustration: 24‐year US analysis reveals rising atrial fibrillation‐related mortality in older adults with Parkinson's disease, highlighting significant disparities by sex, race, and geography. ABSTRACT Background The coexistence of Parkinson's Disease (PD) and Atrial Fibrillation (AF) is increasingly recognized, but the mortality burden and ...
Mohid Zulfiqar, Syed Ahmed Ali Shah, Asim Sajjad, Muhammad Tahir, Wasay Mumtaz Awan, Hermann Yokolo, Muhammad Ahmed   +6 more
wiley   +1 more source

Metabolic syndrome in youth with bipolar spectrum disorders treated with second-generation antipsychotics: baseline results from the community-based pragmatic MOBILITY Trial. [PDF]

Eur Child Adolesc Psychiatry
Higdon C, Welge JA, Crimmins NA, Klein CC, Fornari VM, Sorter MT, Blom TJ, Kurtz BP, Correll CU, DelBello MP.   +9 more
europepmc   +1 more source

Second-Generation Antipsychotics: Looking beyond Efficacy [PDF]

The Canadian Journal of Psychiatry, 2004
openaire   +1 more source

Streamlined One‐Pot Synthesis of Fused Pyrroles: A Three‐Component Approach

ChemistryOpen, Volume 15, Issue 4, April 2026.
New modified pyrrole derivatives, namely tetrahydroindol‐4‐ones and pyrrolo[2,3‐d]pyrimidines, functionalized at position 3, were synthesized through a one‐pot multicomponent condensation. Stabilized dimedone enaminones derived from α‐amino acids and their esters (or 6‐amino‐1,3‐dimethyluracil), arylglyoxals, and methylene‐active compounds ...
Kateryna I. Marchenko, Vladislava I. Grinko, Roman M. Gutzul, Oleksandr S. Kharchenko, Henning J. Jessen, Nadiia N. Kolos   +5 more
wiley   +1 more source

Assessing Research Impact With Bibliometrics and Altmetrics: The Case of the Canadian Network for Observational Drug Effect Studies (CNODES)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 4, April 2026.
ABSTRACT Purpose Our purpose was to measure the research output and impact of the Canadian Network for Observational Drug Effect Studies (CNODES). Methods We used OpenAlex to collect metadata on citation counts for all 115 CNODES articles published between January 2011 and March 2022. We obtained the altmetric scores from Altmetric.com.
Alexandra M. Yip, Ingrid S. Sketris, Samuel A. Stewart, Pauline Reynier, Philippe Mongeon, Kristian B. Filion   +5 more
wiley   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
The topoisomerase I inhibition and antiproliferative activities of phosphorated indenoquinoline derivatives were investigated. The target hybrid quinoline and tetrahydroquinoline compounds were synthesized via a two‐step Povarov‐type cycloaddition.
Alba Rodriguez, Elena Formoso, Birgitta R. Knudsen, Cinzia Tesauro, Maria Fuertes, Concepcion Alonso   +5 more
wiley   +1 more source