Results 221 to 230 of about 37,162 (308)

Second-Generation Antipsychotics Induce Metabolic Disruption in Adipose Tissue-Derived Mesenchymal Stem Cells Through an aPKC-Dependent Pathway. [PDF]

open access: yesCells
Varalda M   +11 more
europepmc   +1 more source

Synthesis of Sulfur Enriched Cyclohexenes via the Tungsten‐Promoted Dearomatization of a Phenyl Sulfone

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 9, 2 March 2026.
A method for synthesizing sulfur‐substituted cyclohexenes is reportedthat leverages the η2‐coordination of a phenyl sulfone to [WTp(NO)(PMe3)] (Tp = trispyrazolylborate). Three sequential protonation and nucleophilic additions to the bound arene, followed by oxidative decomplexation, affords functionalized cyclohexenes bearing sp3‐ and sulfur‐enriched ...
Daniel J. Siela   +3 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, Volume 36, Issue 25, 26 March 2026.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 869-878, March 2026.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

Olanzapine Attenuates the Morphine‐Induced Conditioned Place Preference: The Involvement of the D2‐Like Dopamine Receptors

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
The results of this study demonstrated that olanzapine can inhibit morphine‐induced CPP behavior during the acquisition, expression, and extinction phases. These effects are likely mediated by the inhibition of dopamine receptors and a reduction in D2R protein expression in the HIP.
Farkhondeh Rzazzaghi‐ Firozjaei   +6 more
wiley   +1 more source

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