Results 41 to 50 of about 37,162 (308)

Attitudes towards antipsychotics among patients with schizophrenia on first- or second-generation medications

Indian Journal of Psychological Medicine, 2014
Background: Given the paucity of research in this area, this study attempted to assess attitudes toward antipsychotic medications and its correlates among patients with schizophrenia, either on first-generation antipsychotics (FGAs) or second-generation ...
M S Karthik, Nisha Warikoo, Subho Chakrabarti, Sandeep Grover, Parmanand Kulhara   +4 more
doaj   +1 more source

Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]

, 2014
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core   +3 more sources

Intentional Recreational Abuse of Quetiapine Compared to Other Second-generation Antipsychotics

Western Journal of Emergency Medicine, 2017
Introduction: Case reports and poison center data have demonstrated that the second-generation antipsychotic quetiapine is being obtained and used for recreational abuse.
Lauren Klein, Stacey Bangh, Jon B. Cole
doaj   +1 more source

A case of tardive dyskinesia with paliperidone palmitate

Telangana Journal of Psychiatry, 2015
Background: Tardive dyskinesia is a neurological side effect of long term antipsychotics use. Incidence is common and found to be less prevalent with second generation antipsychotics than the first generation antipsychotics.
Philip Kumar Boyanapally, Nishanth Vemana, Phani Prasant Mulakaluri   +2 more
doaj   +1 more source

Interactions between antiepileptics and second-generation antipsychotics

Expert Opinion on Drug Metabolism & Toxicology, 2012
Pharmacokinetic and pharmacodynamic drug interactions (DIs) can occur between antiepileptics (AEDs) and second-generation antipsychotics (SGAPs). Some AED and SGAP pharmacodynamic mechanisms are poorly understood. AED-SGAP combinations are used for treating comorbid illnesses or increasing efficacy, particularly in bipolar disorder.This article ...
de Leon J, SANTORO, VINCENZA, D'Arrigo C, SPINA, Edoardo   +3 more
openaire   +4 more sources

Adding pre-emptive anticholinergics to antipsychotics: Is it justified?

Industrial Psychiatry Journal, 2022
Anti-psychotics are the mainstay of treatment for Schizophrenia and psychotic disorders. Historically, anticholinergics have been prescribed to prevent or treat extrapyramidal side effects (EPS) associated with first-generation antipsychotics (FGAs ...
Kaushik Chatterjee, Ankit Dangi, Rachit Sharma, Prateek Yadav, Vinay Singh Chauhan, Jyoti Prakash   +5 more
doaj   +1 more source

Minimal-medication approaches to treating schizophrenia [PDF]

, 2009
UK guidelines for treating people diagnosed with schizo phrenia currently emphasise the primacy of antipsychotic medication, with or without psycho-socially based interventions as circumstances dictate.
Aderhold, Agar-Jacomb, Barnes, Bennett, Burston, Calton, Carpenter, Ciompi, Ciompi, Cooper, Davis, Day, Descartes, Digby, Fins, Fulford, Gray, Griesinger, Grisso, Harrow, Helen Spandler, Hogarty, Hyman, Loebel, Mosher, Mosher, Mosher, Pasamanick, Pincus, Podvoll, Porter, Pullen, Rappaport, Rose, Seikkula, Seikkula, Statsny, Tim Calton, Warner, Watkins, Wirt   +40 more
core   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Prescription pattern of antipsychotics in patients with schizophrenia: An observational study at a tertiary care hospital in rural Karnataka

Journal of Psychiatry Spectrum
Background: Schizophrenia is a severe psychiatric condition that affects approximately 24 million people worldwide. The complex pathophysiology of schizophrenia presents various challenges for researchers and doctors.
Nameerah Javed, Benison Binny, Dafney Viola Sequeira, Vinod K. Mathew, Kasthuri Pandiyan   +4 more
doaj   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

Advanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel, Nikolas Ebert, Denis Abu Sammour, Sebastian Graf, Björn C. Fröhlich, Emrullah Birgin, Shad A. Mohammed, Nuh N. Rahbari, Axel Wellmann, Oliver Wasenmüller, Cleo‐Aron Weis, Stefan Schmidt, Carsten Hopf   +12 more
wiley   +1 more source