Results 41 to 50 of about 38,837 (270)

Intentional Recreational Abuse of Quetiapine Compared to Other Second-generation Antipsychotics

Western Journal of Emergency Medicine, 2017
Introduction: Case reports and poison center data have demonstrated that the second-generation antipsychotic quetiapine is being obtained and used for recreational abuse.
Lauren Klein, Stacey Bangh, Jon B. Cole
doaj   +1 more source

Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]

, 2014
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core   +3 more sources

A case of tardive dyskinesia with paliperidone palmitate

Telangana Journal of Psychiatry, 2015
Background: Tardive dyskinesia is a neurological side effect of long term antipsychotics use. Incidence is common and found to be less prevalent with second generation antipsychotics than the first generation antipsychotics.
Philip Kumar Boyanapally, Nishanth Vemana, Phani Prasant Mulakaluri   +2 more
doaj   +1 more source

Adding pre-emptive anticholinergics to antipsychotics: Is it justified?

Industrial Psychiatry Journal, 2022
Anti-psychotics are the mainstay of treatment for Schizophrenia and psychotic disorders. Historically, anticholinergics have been prescribed to prevent or treat extrapyramidal side effects (EPS) associated with first-generation antipsychotics (FGAs ...
Kaushik Chatterjee, Ankit Dangi, Rachit Sharma, Prateek Yadav, Vinay Singh Chauhan, Jyoti Prakash   +5 more
doaj   +1 more source

Minimal-medication approaches to treating schizophrenia [PDF]

, 2009
UK guidelines for treating people diagnosed with schizo phrenia currently emphasise the primacy of antipsychotic medication, with or without psycho-socially based interventions as circumstances dictate.
Aderhold, Agar-Jacomb, Barnes, Bennett, Burston, Calton, Carpenter, Ciompi, Ciompi, Cooper, Davis, Day, Descartes, Digby, Fins, Fulford, Gray, Griesinger, Grisso, Harrow, Helen Spandler, Hogarty, Hyman, Loebel, Mosher, Mosher, Mosher, Pasamanick, Pincus, Podvoll, Porter, Pullen, Rappaport, Rose, Seikkula, Seikkula, Statsny, Tim Calton, Warner, Watkins, Wirt   +40 more
core   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Prescription pattern of antipsychotics in patients with schizophrenia: An observational study at a tertiary care hospital in rural Karnataka

Journal of Psychiatry Spectrum
Background: Schizophrenia is a severe psychiatric condition that affects approximately 24 million people worldwide. The complex pathophysiology of schizophrenia presents various challenges for researchers and doctors.
Nameerah Javed, Benison Binny, Dafney Viola Sequeira, Vinod K. Mathew, Kasthuri Pandiyan   +4 more
doaj   +1 more source

Antipsychotics use in the community of Thessaloniki, Greece [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Under the current financial crisis in Greece, an effort has been made by the Greek health authorities to encourage generic prescribing, in order to lower medicinal cost.
Papaioannidou Paraskevi, Kasviki Paschalina   +1 more
doaj   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Variations of Aripiprazole-Induced Dyskinesia Existing with Concurrent Use of Amantadine and an Anticholinergic Agent in an Elderly Patient

International Journal of Gerontology, 2012
Elderly patients are vulnerable to the adverse neurological effects of antipsychotics, particularly Parkinsonian symptoms and tardive dyskinesia. This vulnerability in the elderly becomes complex and unpredictable when aripiprazole is prescribed to ...
I-Wen Sun, Ying Lin, Shen-Ing Liu, Chau-Shoun Lee   +3 more
doaj   +1 more source