Results 31 to 40 of about 1,228,391 (288)

Word-formation in second language acquisition [PDF]

open access: yes, 2015
This article explores the role of word-formation processes in the acquisition of a second-language lexicon and the relevant concepts from second language acquisition theory, among them the ‘word family’.
Cornelia Tschichold
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fossilization in Adult Second Language Acquisition

open access: yesStudies in Applied Linguistics & TESOL, 2005
Most non-native speakers would agree that it is sometimes frustrating to communicate in another language. Many have embarrassing stories about how they have been misunderstood or have not been able to convey their intended messages at all.
Özlem Pazvant
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Response through the Intentional Arc: Merleau-Ponty, Dreyfus and Second Language Acquisition [PDF]

open access: yes, 2019
Language, when considered as part of the lived experience of human beings, fails to be reduced to mere representation. In line with non-representationalist understandings of the mind and knowledge-how centered understandings of knowledge, purposiveness ...
Burnett, Mia
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Predicting Native Language from Gaze [PDF]

open access: yes, 2017
A fundamental question in language learning concerns the role of a speaker's first language in second language acquisition. We present a novel methodology for studying this question: analysis of eye-movement patterns in second language reading of free ...
Berzak, Yevgeni   +3 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Reaching out to the other side: Formal-linguistics-based SLA and Socio-SLA [PDF]

open access: yes, 2013
Generative linguistics has long been concerned with the linguistic competence of the “ideal speaker-listener, in a completely homogeneous speech-community, who knows its language perfectly” (Chomsky 1965: 3).
Kinzler   +30 more
core   +2 more sources

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