Results 101 to 110 of about 17,700,714 (250)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A study on the oscillation of second-order neutral differential equations in noncanonical form

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
This paper analyzes the oscillation of the second-order neutral differential equation in noncanonical form \[ \left[r(t)\left(\left(x(t)+p(t)x(\pi(t))\right)^{\prime}\right)^{\alpha}\right]^{\prime} + k(t)x^{\beta}(\eta(t))=0.
Ercan Tunç
doaj   +1 more source

On the oscillation of second-order half-linear functional differential equations with mixed neutral term

open access: yesJournal of Taibah University for Science, 2019
In this article, the authors establish new sufficient conditions for the oscillation of solutions to a class of second-order half-linear functional differential equations with mixed neutral term.
Ercan Tunç, Orhan Özdemir
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Collocation methods for a class of second order initial value problems with oscillatory solutions [PDF]

open access: yes, 1993
We derive and analyse two families of multistep collocation methods for periodic initial-value problems of the form y" = f(x, y); y((^x)o) = yo, y(^1)(xo) = zo involving ordinary differential equations of second order in which the first derivative ...
Booth, Andrew S.
core  

Second-order wave diffraction in two dimensions

open access: yes, 1994
A method for constructing the second-order diffraction potential associated with two-dimensional bodies is described. By introducing analytic functions such as the square of the first-order complex velocity and taking their real or imaginary parts ...
Maureen McIver (1247559)
core   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Second-order hidden Markov model.

open access: yes, 2018
Second-order hidden Markov model.
Ying Chen (9697)   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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