Results 121 to 130 of about 2,365,205 (295)

Pragmatic versus structural difficulties in the production of pronominal clitics in French-speaking children with autism spectrum disorder

open access: yesAutism and Developmental Language Impairments, 2018
Background and aims Impaired production of third person accusative pronominal clitics is a signature of language impairment in French-speaking children.
Philippe Prévost   +5 more
doaj   +1 more source

What We Epistemically Owe To Each Other [PDF]

open access: yes, 2019
This paper is about an overlooked aspect—the cognitive or epistemic aspect—of the moral demand we place on one another to be treated well. We care not only how people act towards us and what they say of us, but also what they believe of us.
Basu, Rima
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

You and I, Past and Present. Cognitive Processing of Perspective

open access: yesDiegesis: Interdisziplinäres E-Journal für Erzählforschung, 2016
This article describes an experiment investigating the relationship between deic­tic elements of focalisation and readers’ perspective-taking within imaginative conceptualisations of a fictional narrative scene. The text variables tested here are whether
Andrea Macrae
doaj  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Modes of Knowing

open access: yesFaith and Philosophy, 2009
The rapid, perplexing increase in the incidence of autism has led to a correlative increase in research on it and on normally developing children as well. In this paper I consider some of this research, not only for what it shows us about human cognitive capacities but also for its suggestive implications regarding the ability of science to teach us ...
openaire   +2 more sources

If You Believe You Believe, You Believe. A Constitutive Account of Knowledge of One’s Own Beliefs [PDF]

open access: yes, 2017
Can I be wrong about my own beliefs? More precisely: Can I falsely believe that I believe that p? I argue that the answer is negative. This runs against what many philosophers and psychologists have traditionally thought and still ...
Baumann, Peter
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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