Results 51 to 60 of about 3,878 (155)

"Two tribes": Handaxe shape variation shows distinct regional cultural groups in southeastern Britain between 424 000 and 374 000 BP

Journal of Quaternary Science, EarlyView.
ABSTRACT This paper examines regional and chronological variations in Acheulean handaxe morphology during Marine Isotope Stage 11 (c. 425–365 ka BP) in Britain. Using a data set of 737 handaxes from 13 securely dated sites in East Anglia and the Thames Valley, we apply three‐dimensional geometric morphometric analysis to examine morphological ...
Mark White, Frederick Foulds, Aaron Rawlinson, Ceri Shipton, Rob Davis, Nick Ashton   +5 more
wiley   +1 more source

Aquatic and Littoral Successions in Various Post‐Mining Sites—Patterns and Possible Use in Ecological Restoration

Land Degradation &Development, EarlyView.
ABSTRACT Vegetation succession in aquatic and littoral habitats has received much less attention than terrestrial habitats have. We sampled differently aged successional stages at five different types of post‐mining sites, that is, sandpits, stone quarries, clay quarries, brown coal spoil heaps and black coal subsidences, across the Czech Republic ...
Anna Müllerová, Klára Řehounková, Karel Prach   +2 more
wiley   +1 more source

Differentiating Nonsuicidal Self‐Injury (NSSI) From Suicide Attempts in Adolescents: A Pilot Study

Medicine Bulletin, EarlyView.
ABSTRACT Background Differentiating between nonsuicidal self‐injury (NSSI) and suicide attempts (SA) in adolescents is crucial due to distinct underlying motivations, treatment needs, and potential outcomes associated with each behavior.
María Posada‐Ayala, Ping Wang, Gemma Barroso‐Garcia, Encarnación Donoso‐Navarro, Elena Hernandez‐Alvarez, María Gil‐Ligero, Julián Romero, Silvia Rosado‐Garcia, Antonio José Sánchez‐López, Hilario Blasco‐Fontecilla   +9 more
wiley   +1 more source

bregr: An R Package for Streamlined Batch Processing and Visualization of Biomedical Regression Models

Med Research, EarlyView.
ABSTRACT Regression analysis is essential in biomedical research for exploring relationships between phenotypic or clinical outcomes and diverse predictors. However, constructing multiple univariate and multivariate models is often hindered by the lack of robust tools for batch regression in R, forcing researchers to rely on custom scripts.
Shixiang Wang, Yun Peng, Chenyang Shu, Chunyang Wang, Yuxi Yang, Yankun Zhao, Yanru Cui, Dehua Hu, Jian‐Guo Zhou   +8 more
wiley   +1 more source

Pallidal Evoked Resonant Neural Activity as a Candidate Biomarker for Deep Brain Stimulation in Dystonia

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) targeted to the globus pallidus (GP) can effectively alleviate dystonia symptoms. However, identifying optimal therapeutic stimulation parameters is challenging due to the manual programming process and the paucity of acute effects of DBS on dystonia symptoms.
Kara A. Johnson, Patricia B. Coutinho, Filipe P. Sarmento, Elizabeth Vo, Joshua K. Wong, Justin D. Hilliard, Kelly D. Foote, Coralie de Hemptinne   +7 more
wiley   +1 more source

The Race to Salvage Glucocerebrosidase: Understanding Small‐Molecule Therapies for GBA1‐Associated Parkinsonism

Movement Disorders, EarlyView.
Variants in GBA1, the gene encoding the lysosomal enzyme glucocerebrosidase, cause Gaucher disease and confer an increased risk for parkinsonism. Strategies using small molecules can improve the function of glucocerebrosidase in lysosomes. A clear understanding of the mechanism‐of‐action of these compounds will facilitate development of GBA1‐modulating
Mark J. Henderson, Tiffany C. Chen, Logan M. Glasstetter, Yu Chen, Juan J. Marugan, Ellen Sidransky   +5 more
wiley   +1 more source

Multimodal Imaging Investigation of the Dentato‐Thalamo‐Cortical Pathway in Friedreich's Ataxia

Movement Disorders, EarlyView.
Abstract Background Friedreich's ataxia (FRDA) is a spinocerebellar neurodegenerative disorder. The dentato‐thalamo‐cortical (DTC) pathway, an important cerebellar output involved in motor control, plays a crucial role in the neural mechanisms underlying ataxia symptoms in FRDA.
Yinghua Jing, Imis Dogan, Ravi Dadsena, Jennifer Faber, Jörg B. Schulz, Kathrin Reetz, Sandro Romanzetti, on behalf of the FACROSS study group, Stella A. Lischewski, Kerstin Konrad, Miguel Pishnamaz, Maximillian Praster, Thomas Clavel, Vera Jankowski, Joachim Jankowski, Oliver Pabst, Katharina Marx‐Schütt, Nikolaus Marx, Julia Möllmann, Malte Jacobsen, Juergen Dukart, Simon Eickhoff, Ralf‐Dieter Hilgers   +22 more
wiley   +1 more source

FMRI Approaches to Mapping Cerebrovascular Reactivity: Comparison of Gradient Echo BOLD and Spin Echo BOLD With Arterial Spin Labeling

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To compare markers of cerebrovascular reactivity (CVR) measured with Gradient Echo (GE, T2*w) and Spin‐Echo (SE, T2w) BOLD fMRI with quantitative physiological CVR measured using ASL. Methods CVR, the ability of blood vessels to dilate and increase cerebral blood flow (CBF), can be investigated with ASL fMRI but has a low signal‐to ...
Sara Pomante, Davide Di Censo, Alessandra Caporale, Fabrizio Fasano, Domenico Zacà, Elizabeth Jane Fear, Francesca Graziano, Manuela Carriero, Lucie Renee Raymonde Chalet, Emma Biondetti, Maria Eugenia Caligiuri, Michael Germuska, Richard Geoffrey Wise, Antonio Maria Chiarelli   +13 more
wiley   +1 more source

Effect of population reinforcement method, site, and plant characteristics on early establishment of the rare endemic plant species Minuartia smejkalii

Nordic Journal of Botany, EarlyView.
Many habitat‐specialist plant species have been endangered by fragmentation or destruction of their habitats. Minuartia smejkalii is a serpentinophyte endemic to the Czech Republic. It is highly threatened by recent habitat destruction and fragmentation, calling for effective conservation measures.
Alrun Siebenkäs, Karolína Sučíková, Zuzana Münzbergová, Hana Pánková   +3 more
wiley   +1 more source

Cholecystectomy Is Linked With Lower Respiratory Exchange Ratio and Higher Lipid Oxidation and Sleep Energy Expenditure

Obesity, EarlyView.
ABSTRACT Objective Cholecystectomy (GBX) may alter energy metabolism, but human evidence is limited. We examined whether GBX alters energy expenditure (EE), respiratory exchange ratio (RER), and substrate oxidation. Methods A total of 384 healthy Southwestern Indigenous American adults (222 males, age 28 ± 6 years) were studied, including individuals ...
Beyza N. Aydin, Emma J. Stinson, Helen C. Looker, Peter Walter, Tomás Cabeza de Baca, Jonathan Krakoff, Douglas C. Chang   +6 more
wiley   +1 more source