Results 71 to 80 of about 4,004 (182)

A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia

Movement Disorders, EarlyView.
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson, Isaac Adanyeguh, David J. Arpin, Tetsuo Ashizawa, Benjamin Bender, Fernando Cendes, Xi Chen, Giulia Coarelli, Léo Coutinho, Andreas Deistung, Imis Dogan, Alexandra Durr, Jennifer Faber, for the ESMI MR Study Group, Juan Fernandez‐Ruiz, Mónica Ferreira, Marcondes C. França, Sophia L. Göricke, Shuo Han, Thomas Klockgether, Chen Liu, Jun Luo, Alberto R.M. Martinez, Sergio E. Ono, Chiadi U. Onyike, Gülin Öz, for the EUROSCA MR Study Group, Henry Paulson, Jerry L. Prince, Kathrin Reetz, Thiago J.R. Rezende, Matthis Synofzik, Hélio A. Ghizoni Teive, Sophia I. Thomopoulos, Paul M. Thompson, Dagmar Timmann, David Vaillancourt, Bart van de Warrenburg, Judith van Gaalen, Xingang Wang, Philipp Wegner, Sarah H. Ying, Ian H. Harding, Carlos R. Hernandez‐Castillo   +43 more
wiley   +1 more source

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

SimulScan and Partial Least Squares: Visualizing Swallowing Through Functional and Dynamic Imaging Correlations

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Swallowing involves the precise coordination of muscles and brain areas and can be disrupted in a variety of neurological conditions. Current methods to visualize swallowing cannot examine both the biomechanics and brain activity associated with specific swallowing events.
Bradley P. Sutton, Anthony Bosshardt, Ching‐Hsuan Peng, Ololade T. Adetula, Jiyoon Kim, Riwei Jin, Vaishnavi Krishna, William G. Pearson Jr., Zhongming Liu, Georgia A. Malandraki   +9 more
wiley   +1 more source

Effect of population reinforcement method, site, and plant characteristics on early establishment of the rare endemic plant species Minuartia smejkalii

Nordic Journal of Botany, EarlyView.
Many habitat‐specialist plant species have been endangered by fragmentation or destruction of their habitats. Minuartia smejkalii is a serpentinophyte endemic to the Czech Republic. It is highly threatened by recent habitat destruction and fragmentation, calling for effective conservation measures.
Alrun Siebenkäs, Karolína Sučíková, Zuzana Münzbergová, Hana Pánková   +3 more
wiley   +1 more source

Fruit‐quality tradeoffs generate asymmetry in plant reliance on mutualistic frugivores

Oikos, EarlyView.
Seed dispersal is a fundamental ecological process influencing the evolution of plant life‐history strategies. In fleshy‐fruited plants dispersed by mutualistic frugivores, variation in fruit traits among closely related species may shape the temporal and spatial dynamics of dispersal events critical to population success.
João Vitor S. Messeder, Tomás A. Carlo
wiley   +1 more source

Powering RCTs for Marginal Effects With GLMs Using Prognostic Score Adjustment. [PDF]

Stat Med
Højbjerre-Frandsen E, van der Laan MJ, Schuler A.   +2 more
europepmc   +1 more source

Age ratio in groups of a social ungulate affects epizoochorous dispersal and diaspore exchanges

Oikos, EarlyView.
Animal‐mediated seed dispersal is a key process in plant population dynamics, species distribution and ecosystem functioning. As long‐distance dispersal agents, ungulates help to maintain native plant populations facing abiotic changes in their habitat and habitat fragmentation or habitat loss.
Antoine Roux, Cloé Balson, Morgane Audiguier, Marie Battista, Didier Marcon, Olivier Pays, Christophe Baltzinger   +6 more
wiley   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

Oikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining, Cameron M. Hudson, Jernej Bravničar, Antonella Carosi, Gaël P. J. Denys, Philine G. D. Feulner, Žiga Fišer, Hanna Rosinger, Verena Saladin, Linda Zanella, Davor Zanella, Catherine L. Peichel, Blake Matthews   +12 more
wiley   +1 more source

Optimizing short-channel regression in fNIRS: an empirical evaluation with ecological audiovisual stimuli. [PDF]

Neurophotonics
Lemaire Y, Barone P, Strelnikov K, Deguine O, Caclin A, Ginzburg J.   +5 more
europepmc   +1 more source