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Higher complement C4 gene copy number constitutes a shared genetic risk factor for giant cell arteritis and IgA vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +296 more
wiley +1 more source

Associations Between Comorbidities, Developmental Status, and Disease Severity in Children With Autism Spectrum Disorder: A Multicenter Cross‐Sectional Study in China

Autism Research, EarlyView.
ABSTRACT Children with autism spectrum disorder (ASD) frequently present with co‐occurring conditions that can influence autism symptom severity and complicate clinical management. However, studies with clinician‐confirmed diagnoses in non‐Western populations remain limited.
Dizhou Pang +25 more
wiley +1 more source

Dispersion relations of Nambu-Goldstone modes at finite temperature and density

, 2015
We discuss the dispersion relations of Nambu-Goldstone (NG) modes associated with spontaneous breaking of internal symmetries at finite temperature and/or density.
Hayata, Tomoya, Hidaka, Yoshimasa
core +1 more source

Mid‐Domain Effect and Wooded Habitat Shape Mediterranean Reptile Communities

Biological Diversity, EarlyView.
Analyzing a large number of reptiles observed across protected areas in Central Italy, we tested whether the mid‐domain effect explains hump‐shaped richness–elevation patterns. Species richness was best predicted by the combined influence of geometric constraints and woodland cover, revealing two contrasting species clusters and offering a robust ...
Daniele Dendi +3 more
wiley +1 more source

Spatial metrics in fire ecology: seeking consistency amidst complexity

Biological Reviews, EarlyView.
ABSTRACT Technological advances, including remote sensing, have led to a proliferation of metrics used in ecological studies to examine spatial patterns of fire regimes and their ecological effects. Researchers can use many different metrics to analyse spatial variation in both fire events and resulting fire regimes, including fire size, shape ...
Alexander R. Carey +5 more
wiley +1 more source

Venture Funding: Signals of Environmental Orientation and Their Interplay With Investor‐ and Country‐Level Characteristics

Business Strategy and the Environment, EarlyView.
ABSTRACT Environmentally oriented ventures pursue a dual mission: to create both environmental and financial value. This dual mission adds complexity and can influence ventures' funding prospects, as investors mostly pursue financial motivations.
David Flore +2 more
wiley +1 more source

Improved variable selection with Forward-Lasso adaptive shrinkage

, 2011
Recently, considerable interest has focused on variable selection methods in regression situations where the number of predictors, $p$, is large relative to the number of observations, $n$. Two commonly applied variable selection approaches are the Lasso,
James, Gareth M., Radchenko, Peter
core +1 more source

Crafted Responsibility: How Handmade Language Shapes Social Media Engagement for Socially (Ir)Responsible Luxury Fashion Brands

Journal of Consumer Behaviour, EarlyView.
ABSTRACT This research examines how the disclosure of production cues interacts with corporate social responsibility cues to influence social media engagement in luxury fashion. Two complementary field studies analyse marketer‐generated Facebook posts from luxury fashion brands, providing large‐scale empirical evidence of a real‐world impact on ...
Tuba Degirmenci, Frank Mathmann, Gary Mortimer +2 more
wiley +1 more source

Environmental and local habitat variables as predictors of trophic interactions in subtidal rocky reefs along the SE Pacific coast

Ecography, EarlyView.
Temperature generally drives latitudinal patterns in the strength of trophic interactions, including consumption rates. However, local community and other environmental conditions might also affect consumption, disrupting latitudinal gradients, which results in complex large‐scale patterns.
Catalina A. Musrri +6 more
wiley +1 more source

Harnessing the power of machine and deep learning for transferring joint species distribution models considering the structure of biotic interactions

Ecography, EarlyView.
The transferability of single or joint species distribution models ((j)SDMs) depends on their ability to predict beyond the observed environmental range and to remain consistent despite shifts in biotic interactions. Transfer accuracy may be improved by recent advances in the application of deep learning that provide greater flexibility and potentially
Marco Basile +44 more
wiley +1 more source

general linear methods glm
nordsieck vectors/methods
rk-starters

variable stepsize