Results 31 to 40 of about 12,779,859 (228)

A New Design Criterion to Improve the Intact Stability of Galician Small Fishing Vessels

Journal of Marine Science and Engineering, 2020
The first technical factor involved in maritime accidents is related to the lack of intact stability. The current stability criterion, based on fixing a minimum value for each of the different static and dynamic righting arms, is not regarded as ...
Jesús Alvite-Castro, José A. Orosa, Diego Vergara, Ángel M. Costa, Rebeca Bouzón   +4 more
doaj   +1 more source

Operational measures in second generation intact stability criteria: effect of source of environmental data

, 2021
The framework of second generation intact stability criteria allows designing a vessel for a specific operational area, by embedding area-specific environmental conditions.
Gabriele Bulian, Andrea Orlandi
core  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

State-of-the-art and prospects of direct stability assessment methods for second-generation intact stability criteria

Zhongguo Jianchuan Yanjiu
Intact stability of ships in waves is a fundamental guarantee for navigation safety. The direct stability assessment methods associated with the Second Generation Intact Stability Criteria (SGISC) remain undeveloped and have become a key focus of current
Min GU, Jilong CHU, Peijie ZHANG, Shuxia BU   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Comparison of Numerical Simulations and Model Experiments on Parametric Roll in Irregular Seas

Journal of Marine Science and Engineering, 2020
The recently finalised Second Generation Intact Stability Criteria (SGISC), produced by the International Maritime Organisation (IMO), contain a level 3 assessment, the so-called Direct Stability Assessment (DSA). This assessment can be carried out using
Geert Kapsenberg, Clève Wandji, Bulent Duz, Sungeun (Peter) Kim   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Sensibility analysis and further development for dead ship stability criteria based on local linearization method

Zhongguo Jianchuan Yanjiu, 2018
[Objectives] The dead ship stability, which is defined as a ship losing its power and rolling after turning into beam seas, is recognized as a dangerous stability failure mode.
WANG Tinghao, GU Xiechong, MA Chengyuan, MA Ning   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source