Results 31 to 40 of about 13,309,130 (242)

Current Status of the 2nd Generation of Intact Stability: Investigation of the Pure Loss of Stability and Parametric Roll Mode

한국해양공학회지, 2020
A review of the 2nd generation of intact stability by the International Maritime Organization is performed. The main issues with the new stability criteria are reviewed.
Jaeho Chung, Dong Min Shin, Won-Don Kim, Byung Young Moon   +3 more
doaj   +1 more source

A New Design Criterion to Improve the Intact Stability of Galician Small Fishing Vessels

Journal of Marine Science and Engineering, 2020
The first technical factor involved in maritime accidents is related to the lack of intact stability. The current stability criterion, based on fixing a minimum value for each of the different static and dynamic righting arms, is not regarded as ...
Jesús Alvite-Castro, José A. Orosa, Diego Vergara, Ángel M. Costa, Rebeca Bouzón   +4 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Application of 2nd generation intact stability criteria on naval ships

, 2016
The second generation intact stability criteria are currently under finalization and validation at the IMO. These criteria are organized in five stability failure modes and three levels of vulnerability assessment in each failure mode.
Petacco, Nicola, Grinnaert, Fran(c(c))ois, Gualeni, Paola, Billard, Jean-Yves, Laurens, Jean-Marc   +4 more
core   +2 more sources

State-of-the-art and prospects of direct stability assessment methods for second-generation intact stability criteria

Zhongguo Jianchuan Yanjiu
Intact stability of ships in waves is a fundamental guarantee for navigation safety. The direct stability assessment methods associated with the Second Generation Intact Stability Criteria (SGISC) remain undeveloped and have become a key focus of current
Min GU, Jilong CHU, Peijie ZHANG, Shuxia BU   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

A Comparison of Numerical Simulations and Model Experiments on Parametric Roll in Irregular Seas

Journal of Marine Science and Engineering, 2020
The recently finalised Second Generation Intact Stability Criteria (SGISC), produced by the International Maritime Organisation (IMO), contain a level 3 assessment, the so-called Direct Stability Assessment (DSA). This assessment can be carried out using
Geert Kapsenberg, Clève Wandji, Bulent Duz, Sungeun (Peter) Kim   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Numerical Method on Large Roll Motion in Beam Seas Under Intact and Damaged Conditions

Journal of Marine Science and Engineering
The second-generation intact stability criteria, including five stability failure modes, were approved by the International Maritime Organization (IMO) in 2020, and it is an urgent task to develop the numerical method for the significant roll motion ...
Jiang Lu, Yanjie Zhao, Chao Shi, Taijun Yu, Min Gu   +4 more
doaj   +1 more source