Results 51 to 60 of about 421,004 (299)
BMC Nutrition, 2020 Background Primary health care data have shown that most patients who were treated for overweight or obesity by a dietitian did not accomplish the recommended treatment period.
Lisa D. M. Verberne +3 more
doaj +1 more source
The incomplete hieroglyphs at the end of the Second Intermediate Period [PDF]
, 2008 This article attempts a historical, archaeological and social analysis of the practice of mutilating hieroglyphs apparent from the end of the Middle Kingdom and then continues throughout the Second Intermediate Period.
MINIACI, GIANLUCA
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Overweight and Obesity Among Children and Adolescents in Baladrouz City
Diyala Journal of Medicine, 2019 Background:Obesity in children and adolescents is one of the most serious public health challenges of the 21st century because of the effects of future morbidity.
Wathiq Hassan Farman, Hameed M Majeed
doaj +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Status and trend of tree growth and mortality rate at the CONECOFOR plots, 1997-2004
Annals of Silvicultural Research, 2013 The circumference of trees in the CONECOFOR permanent monitoring plots (PMPs) were measured by three surveys carried out in 1997, 2000 and 2005. Plots were arranged into forest types according to tree species, management system and stand structure: beech
Gianfranco Fabbio +3 more
doaj +1 more source
Educational attainment and second births in Romania [PDF]
This study investigates the effect of educational attainment and educational enrolment on the risks of second birth in Romania, using data from the Generations and Gender Survey of 2005.
Cornelia Muresan
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