Results 61 to 70 of about 11,938,074 (248)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Genotyping and evaluation of antimicrobial susceptibility of Enterococcus species from Turkey
Journal of Infection in Developing Countries, 2007 Background: The aim of this study was to investigate the changes with respect to antibacterial resistance and genotype of Enterococcus species isolated in a university hospital during two periods five years apart.Methodology: 321 strains of Enterococcus ...
Yasemin Ersoy,1 Riza Durmaz,2 Mehmet Firat,1 Zeynep Cizmeci,2 and Baris Otlu2
doaj
PLoS ONEThe huge volcanic eruption at Thera (Santorini), situated in the Aegean Sea, occurred within the Late Minoan IA archaeological period. However, its temporal association with Egyptian history has long been a controversial subject.
Hendrik J Bruins +1 more
doaj +1 more source
Intermediate b final exam v1 [PDF]
, 2010 Written exam for students who have completed Units 8C to 12 in the Face2Face Intermediate Series published by Cambridge University ...
Pedley, Emma
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Scientific World Journal, 2012 Temperature and salinity outputs from ECCO (years 93–09) and GLORYS (years 03–09) models have been used to compute the thermohaline and steric sea level trends in the surface (0–150 m), intermediate (150 m–600 m), and deep (600 m–bottom) layers of the ...
F. Javier Soto-Navarro +1 more
doaj +1 more source
Education and second birth rates in Denmark 1981-1994 [PDF]
A high educational attainment is shown to have a positive effect on second birth rates for Danish one-child mothers during the period 1981-94. We examine whether a time-squeeze is a possible explanation: due to the longer enrolment in the educational ...
Mette Gerster +3 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source