Results 61 to 70 of about 1,711,443 (299)

Formation of larynx topographic-anatomic relations with neck organs and structures in the intermediate fetal period of ontogenesis [PDF]

Наука и инновации в медицине, 2019
Objectivesto present topographic and anatomic characteristics of the larynx relationship with neck organs and structures in the intermediate fetal period of human ontogenesis.
Elena D. Lutsay, Maksim I. Anikin, Nuria I. Murtazina   +2 more
doaj   +1 more source

Direct Detection of the Close Companion of Polaris with the Hubble Space Telescope

, 2008
Polaris, the nearest and brightest classical Cepheid, is a single-lined spectroscopic binary with an orbital period of 30 years. Using the High Resolution Channel of the Advanced Camera for Surveys onboard the Hubble Space Telescope (HST) at a wavelength
Anderson, Bono, Bono, Bono, Bono, Bono, Brian D. Mason, Bruntt, Caputo, Chiaberge, Dimitar Sasselov, Edmund Nelan, Evans, Evans, Feast, Fernie, Gail H. Schaefer, Giuseppe Bono, Harmanec, Howard E. Bond, Kamper, Keller, Keller, Margarita Karovska, Mason, Meynet, Nancy Remage Evans, Natale, Neilson, Nieuwenhuijzen, Nordgren, Pietrinferni, Reimers, Turner, Wielen   +34 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Second Intermediate Period [PDF]

, 2009
  +5 more sources

Trade and synchronization in a multi-country economy [PDF]

, 2011
Substantial evidence suggests that countries with stronger trade linkages have more synchro- nized business cycles. The standard international business cycle framework cannot replicate this finding, uncovering the trade-comovement puzzle.
Juvenal , Luciana, Santos Monteiro, Paulo   +1 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Genotyping and evaluation of antimicrobial susceptibility of Enterococcus species from Turkey

Journal of Infection in Developing Countries, 2007
Background: The aim of this study was to investigate the changes with respect to antibacterial resistance and genotype of Enterococcus species isolated in a university hospital during two periods five years apart.Methodology: 321 strains of Enterococcus ...
Yasemin Ersoy,1 Riza Durmaz,2 Mehmet Firat,1 Zeynep Cizmeci,2 and Baris Otlu2
doaj  

The Minoan Thera eruption predates Pharaoh Ahmose: Radiocarbon dating of Egyptian 17th to early 18th Dynasty museum objects.

PLoS ONE
The huge volcanic eruption at Thera (Santorini), situated in the Aegean Sea, occurred within the Late Minoan IA archaeological period. However, its temporal association with Egyptian history has long been a controversial subject.
Hendrik J Bruins, Johannes van der Plicht   +1 more
doaj   +1 more source

Model Thermohaline Trends in the Mediterranean Sea during the Last Years: A Change with Respect to the Last Decades?

The Scientific World Journal, 2012
Temperature and salinity outputs from ECCO (years 93–09) and GLORYS (years 03–09) models have been used to compute the thermohaline and steric sea level trends in the surface (0–150 m), intermediate (150 m–600 m), and deep (600 m–bottom) layers of the ...
F. Javier Soto-Navarro, Francisco Criado-Aldeanueva   +1 more
doaj   +1 more source