Results 71 to 80 of about 1,711,443 (299)

Economic growth in England, 1250-1850: Some new estimates using a demand side approach [PDF]

open access: yes, 2011
Using the demand side approach we construct a new set of estimates of per capita agricultural output and per capita GDP for England over the period 1250-1850.
Nuvolari, Alessandro
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Central Bank Transparency and Financial Market Expectations: The Case of Emerging Markets [PDF]

open access: yes
In this paper, we study how central bank transparency influences the formation of money market expectations in emerging markets. The sample covers 25 countries for the period from January 1998 to December 2009.
Matthias Neuenkirch
core  

Hyksos, Egipcios, Nubios: algunas consideraciones sobre el II Período Intermedio y la convivencia entre los distintos grupos étnicos [PDF]

open access: yes, 1999
This article reviews some questions of the political and social history of the the Second Intermediate Period. The first part is based on recent discussion about the terminology related to the period, and the convenience or unconvenience of using certain
Vivas Sáinz, Inmaculada
core   +2 more sources

A dynamic programming approach to constrained portfolios [PDF]

open access: yes, 2011
This paper studies constrained portfolio problems that may involve constraints on the probability or the expected size of a shortfall of wealth or consumption.
Kraft, Holger, Steffensen, Mogens
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

A THEORY OF DIGITAL DIVIDE: WHO GAINS AND LOSES FROM TECHNOLOGICAL CHANGES? [PDF]

open access: yes
This paper attempts to answer the question: How does the income gap between workers and capitalists evolve over time in the period of ITC and globalization increasing international technology creation and transfers?
Yong Jin Kim
core  

Pulsation-triggered mass loss from AGB stars: the 60-day critical period

open access: yes, 2016
Low- and intermediate-mass stars eject much of their mass during the late, red giant branch (RGB) phase of evolution. The physics of their strong stellar winds is still poorly understood.
McDonald, Iain, Zijlstra, Albert
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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