Results 81 to 90 of about 1,711,443 (299)

An EUV Study of the Intermediate Polar EX Hydrae

, 2002
On 2000 May 5, we began a large multi-wavelength campaign to study the intermediate polar, EX Hydrae. The simultaneous observations from six satellites and four telescopes were centered around a one million second observation with EUVE.
Beuermann K., Cordova F. A., Hellier C., Hellier C., Hellier C., Kim Y., Kim Y., Kunegunda E. Belle, Mark E. Huber, Martin M. Sirk, Mewe R., Reinsch K., Rosen S. R., Rosen S. R., Siegel N., Singh J., Steve B. Howell, Wood J.   +17 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Non-native gobies facilitate the transmission of Bucephalus polymorphus (Trematoda)

Parasites & Vectors, 2015
Background Introduced species can modify local host-parasite dynamics by amplifying parasite infection which can ‘spill-back’ to the native fauna, whether they are competent hosts for local parasites, or by acting as parasite sinks with ‘dilution’ of ...
Markéta Ondračková, Iveta Hudcová, Martina Dávidová, Zdeněk Adámek, Martin Kašný, Pavel Jurajda   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploration of the pyramid complex of King Djedkare: season 2018 [PDF]

Pražské Egyptologické Studie, 2019
During the latest fieldwork in the pyramid complex of King Djedkare in the 2018 season, the Egyptian mission focused oncleaning and documentation of the central and northern parts of the king’s funerary temple, including the open courtyard (T.e), and the
Mohamed Megahed, Peter Jánosi, Hana Vymazalová   +2 more
doaj  

Learning Spanish online : emotions and identity in role-play settings : a thesis submitted in fulfilment of the requirements for the degree of Master of Philosophy in Second Language Teaching, Massey University [PDF]

, 2017
This study focuses on the dynamic interaction between the learner, the context, and the target language using as its framework the learner-context interface model (White 1999, 2003, 2005; White, Direnzo & Bortolotto, 2016).
Direnzo, Elida Raquel
core  

Evaluating Historical Episodes using Shock Decompositions in the DSGE Model [PDF]

, 2020
We present alternative methods for calculating and interpreting the influence of exogenous shocks on historical episodes within the context of DSGE models.
Aligishiev, Z., Ben-Gad, M., Pearlman, J.   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Intravesical chemotherapy in BCG waiting period may prolong time to recurrence for high-risk NMIBC patients

BMC Cancer
Purpose This study aimed to determine whether administering intravesical chemotherapy (IVC) during the Bacillus Calmette - Guérin (BCG) waiting period after the second TURBT improves the recurrence-free survival (RFS) of patients with non - muscle ...
Zhen Li, Zewei Wang, Jiyue Wu, Feilong Zhang, Lijian Gan, Wei Wang, Hailong Li, Ling Gu   +7 more
doaj   +1 more source