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Second-Messenger Systems Coupled to Metabotropic Glutamate Receptors
1994Glutamate and other excitatory amino acids (EAAs) have long been known to increase the levels of various second-messenger systems in different nervous system preparations. However, until recent years, these effects were generally held to be secondary to activation of glutamate-gated cation channels, and subsequent increases in neurotransmitter release ...
P. Jeffrey Conn +2 more
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Second messenger systems and mood disorders
Current Opinion in Psychiatry, 1996Jerry J. Warsh, Peter P. Li
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Effects of general anaesthetics on second messenger systems.
European journal of anaesthesiology, 1995This paper focuses on the potential role of second messenger systems as general anaesthetic targets. Intracellular free calcium, cyclic nucleotides (cAMP, cGMP), inositol polyphosphates, the protein kinase-activating second messenger diacylglycerol, and the transducing G proteins involved in receptor-coupled second messenger pathways have important ...
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