Results 131 to 140 of about 18,143,287 (301)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

IMMUNOLOGICAL PROFILE OF SEROUS OVARIAN CARCINOMA AND DUCTAL BREAST CARCINOMA

open access: yesПаёми Сино
Objective: To evaluate the immunological profile of serous ovarian carcinoma and ductal breast carcinoma, as well as the activity of apoptotic markers as a prognostic factor of sensitivity to immunotherapy. Methods: The study included 53 patients with
Golovkin Ilya Olegovich   +5 more
doaj   +1 more source

Pure second-order logic.

open access: yesNotre Dame Journal of Formal Logic, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Int. Sig. Proc. Workshop on Higher Order Statistics, Chamrouse, France, July 1991.

open access: yes, 2007
Direction finding techniques are usually based on the 2ndorder statistics of the received data. In this paper, we propose a MUSIC-like direction finding algorithm which uses a matrix-valued statistic based on the contraction of the 4thorder cumulant ...
Second-Order Versus Fourth-Order
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

LMI based Stability and Stabilization of Second-order Linear Repetitive Processes

open access: yes, 2010
This paper develops new results on the stability and control of a class of linear repetitive processes described by a second-order matrix discrete or differential equation.
Dabkowski, P   +3 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Second-order approximation for adaptive regression estimators. [PDF]

open access: yes
We derive asymptotic expansions for semiparametric adaptive regression estimators. In particular, we derive the asymptotic distribution of the second-order effect of an adaptive estimator in a linear regression whose error density is of unknown ...
Linton, Oliver, Xiao, Zhijie
core  

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