Results 121 to 130 of about 3,965,692 (312)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Pengujian model second order pada dimensi-dimensi citra toko

open access: yesJurnal Siasat Bisnis, 2017
Penelitan tentang dimensi citra toko umumnya terbatas pada penggunaan variabel laten yang diukur melalui satu tahap (single order), padahal indikator dari citra toko sangat variatif dan komplek.
Siti Saroh
doaj   +1 more source

Pure second-order logic.

open access: yesNotre Dame Journal of Formal Logic, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

CZF and Second Order Arithmetic

open access: yesAnnals of Pure and Applied Logic, 2006
CZF + Separation is shown to be equiconsistent with second-order arithmetic, using realizability.
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Review of second-order models for adsorption systems

open access: yes, 2009
[[abstract]]Applications of second-order kinetic models to adsorption systems were reviewed. An overview of second-order kinetic expressions is described in this paper based on the solid adsorption capacity.
Ho, Y.S.
core  

Second-order Dataframe

open access: yes, 2016
Raw logistic regression data (second-order scale of selection) for leopards Panthera ...
Julien Fattebert (720565)   +21 more
core   +1 more source

Metacommunication as Second Order Communication

open access: yesKOME: An International Journal of Pure Communication Inquiry, 2017
By giving full emphasis to the impossibility of not to communicate, the first axiom of communication stresses how communication is an event not subject to cessation.
Samuel Mateus
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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