Results 41 to 50 of about 1,559,486 (311)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Contractions of 2D 2nd Order Quantum Superintegrable Systems and the Askey Scheme for Hypergeometric Orthogonal Polynomials [PDF]
, 2013 We show explicitly that all 2nd order superintegrable systems in 2 dimensions are limiting cases of a single system: the generic 3-parameter potential on the 2-sphere, S9 in our listing.
Willard Miller Jr. +8 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
On Nonresonance Problems of Second-Order Difference Systems
Advances in Difference Equations, 2008 Let be an integer with , and let . We study the existence and uniqueness of solutions for the following two-point boundary value problems of second-order difference systems: , , where is a potential function satisfying and some nonresonance ...
Ma Ruyun, Luo Hua, Gao Chenghua
doaj +2 more sources
Nontrivial solutions of second-order singular Dirichlet systems
Boundary Value Problems, 2017 We study the existence of nontrivial solutions for second-order singular Dirichlet systems. The proof is based on a well-known fixed point theorem in cones and the Leray-Schauder nonlinear alternative principle. We consider a very general singularity and
Jin Zhao, Yanchao Wang
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Periodic solutions for second order Hamiltonian systems
Le Matematiche, 2011 In this paper we present some recent multiplicity results for a class of second order Hamiltonian systems. Exploiting the variational structure of the problem, it will be shown how the existence of multiple, even infinitely many, periodic solutions can ...
Giuseppina D'Aguì, Roberto Livrea
doaj