Results 61 to 70 of about 1,559,486 (311)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

H infinity control design for generalized second order systems based on acceleration sensitivity function [PDF]

open access: yes, 2008
This article presents an Hinfinty control design method based on the Acceleration Sensitivity (AS) function. This approach can be applied to any fully actuated generalized second order system. In this framework, classical modal specifications(pulsations /
Carpentier, Benjamin   +3 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Switched Convergence of Second-Order Switched Homogeneous Systems

open access: yesAbstract and Applied Analysis, 2013
This paper studies the stabilization of second-order switched homogeneous systems. We present results that solve the problem of stabilizing a switched homogeneous system; that is, we establish necessary and sufficient conditions under which the ...
Carmen Pérez, Francisco Benítez
doaj   +1 more source

QUANTIZATION OF SINGULAR SYSTEMS WITH SECOND-ORDER LAGRANGIANS [PDF]

open access: yesModern Physics Letters A, 2002
The path integral formulation of singular systems with second-order Lagrangians is constructed by using the canonical method. The path integral quantization of Podolsky electrodynamics is studied.
openaire   +2 more sources

Optimizing second-order differential equation systems

open access: yesElectronic Journal of Differential Equations, 2011
In this article we study some continuous versions of the Fletcher-Reeves iteration for minimization described by a system of second-order differential equations.
Tamas Hajba
doaj  

Identification of first and second order systems by reset control

open access: yesRevista Iberoamericana de Automática e Informática Industrial RIAI, 2020
The article presents a method for the identification of first and second order processes with time delay using reset controllers in the absence of disturbances.
S. Zaragoza, J. Sanchez, A. Baños
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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