Results 111 to 120 of about 4,887,838 (285)

Method of locating persons in distress [PDF]

open access: yes, 1977
A method for locating any person in distress in a selected area on the surface of the earth who has deployed passive radio frequency (RF) reflectors in a predetermined arrangement is analyzed.
Sivertson, W. E., Jr.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Adoption by Lesbian and Gay People: The Use and Mis-Use of Social Science Research [PDF]

open access: yes, 1995
In the past twenty years, openly lesbian and gay people have joined in the evolving national dialogue, within the law and elsewhere, about adoption.
Elovitz, Marc E.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Sprawozdanie ze zdalnego seminarium „Transmedial Second-Person Narratives”

open access: yesZagadnienia Rodzajów Literackich, 2023
Magdalena Rembowska-Płuciennik
doaj   +1 more source

The answers are within me. An evaluation of a person centred counselling service for men at HMP Doncaster who have had experience of domestic violence 2005-2007 [PDF]

open access: yes, 2008
This report is the second year evaluation of the person centred counselling service for male victims and perpetrators of domestic violence at HMP Doncaster in 2006/7.
Cadet, N.   +3 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Monte Carlo Methods for Top-k Personalized PageRank Lists and Name Disambiguation [PDF]

open access: yes, 2010
We study a problem of quick detection of top-k Personalized PageRank lists. This problem has a number of important applications such as finding local cuts in large graphs, estimation of similarity distance and name disambiguation. In particular, we apply
Danil Nemirovsky   +5 more
core   +8 more sources

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