Results 61 to 70 of about 4,256,315 (311)

Mutant p53 and cyclin A1 protein expression in primary laryngeal squamous cell carcinomas do not correlate to second primary tumours of the head and neck [PDF]

, 2009
Background: Field cancerization is a feature of head and neck squamous cell carcinoma. No biological marker in the index tumour has been correlated to the development of second primary tumours (SPT).
Rees, Charles G. G., Sarah Eggleton, Eggleton, Sarah, Yang, Jia-Lin, Salardini, Arash, Russell, Pamela J., Smee, Robert, Arash Salardini, Jia‐Lin Yang, Russell, Pamela, Farhadieh, Ross D., Pamela J. Russell, Charles G. G. Rees, Farhadieh, Ross, Rees, Charles, Ross D. Farhadieh, Robert Smee   +16 more
core   +1 more source

Second primary cancers in patients with urothelial cancers [PDF]

Investigative and Clinical Urology, 2016
Purpose: To investigate the second primary cancers (SPCs) in patients with urothelial cancer (UC). Materials and Methods: The records of 2,339 patients whose UC was diagnosed between January 1974 and December 2012 were reviewed.
Ali Feyzullah Şahin, Muammer Altok, Fırat Akdeniz, Güner Yıldız, Rauf Taner Divrik   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Second annual school congress [PDF]

, 1984
not ...
Primary Point
core  

Options for early breast cancer follow-up in primary and secondary care : a systematic review [PDF]

, 2012
Background Both incidence of breast cancer and survival have increased in recent years and there is a need to review follow up strategies. This study aims to assess the evidence for benefits of follow-up in different settings for women who have had ...
Peter Donnelly, Dunn, Janet A., Dunn Janet, Donnelly Peter, Frances Taggart, Taggart Frances, Taggart, Frances M., Donnelly, Peter K., Janet Dunn   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Second language anxiety among year 5 primary school learners in SK King George V [PDF]

, 2013
It is believed that learners learning English as a second language class are having difficulties where they tend to be more conscious and anxious during the learning and teaching process.
Mohd. Yusof, Siti Yasmin
core  

Second primary malignancies in colorectal cancer patients

Scientific Reports, 2021
The prevalence of second primary malignancies (SPMs) in the western world is continually increasing with the risk of a new primary cancer in patients with previously diagnosed carcinoma at about 20%.
Jana Halamkova, Tomas Kazda, Lucie Pehalova, Roman Gonec, Sarka Kozakova, Lucia Bohovicova, Dagmar Adamkova Krakorova, Ondrej Slaby, Regina Demlova, Marek Svoboda, Igor Kiss   +10 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source