Results 71 to 80 of about 4,256,315 (311)
Primary modern foreign languages: an overview of recent research, key issues and challenges for educational policy and practice [PDF]
, 2005 There has never been a UK-wide policy for primary modern foreign language provision. Scotland, which has for many years managed its educational affairs autonomously, introduced foreign languages into its primary schools over a decade ago.
Lindsay, G +9 more
core +1 more source
TrialsBackground Digitally delivered weight loss programmes can provide a convenient, potentially cheaper, and scalable treatment option for people who may need to lose weight.
Gina M. Wren +7 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A meta-analysis of second language cloze testing research [PDF]
, 2008 Numerous studies have accumulated over the last forty years in which second language testing researchers have examined various cloze test characteristics, including what cloze tests are measuring, under what conditions, and for what type of learners.
Koyama, Dennis, Watanabe, Yukiko
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Moving from primary to secondary education: an investigation into the effect of primary to secondary transition on motivation for language learning and foreign language proficiency [PDF]
, 2014 Despite the fact that the primary languages initiative was not made compulsory in 2011, excellent progress has been made in implementing primary language teaching in the majority of English schools.
Courtney, Louise Mary
core
Lung Cancer: Targets and Therapy, 2018 Nadine Abdallah,1 Misako Nagasaka,2,3 Eman Abdulfatah,4 Dongping Shi,4 Antoinette J Wozniak,2 Ammar Sukari2 1Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA; 2Department of Oncology, Barbara Ann Karmanos Cancer Institute,
Abdallah N +5 more
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Second Primary Tumors in Retinoblastoma [PDF]
, 2014 Advances in the diagnosis and treatment of retinoblastoma have vastly improved patient outcomes. In developed countries, the most common cause of death in patients with heritable retinoblastoma is now a second primary tumor occurring in retinoblastoma ...
Harbour, J. William +3 more
core +1 more source
Journal of Family Medicine and Primary CarePatients diagnosed with cancer remain at risk of developing subsequent primary malignancies due to genetic predisposition, environmental factors, and improved survival associated with advances in diagnosis and treatment. Understanding the pattern of dual
Ubaid Jeelani +8 more
doaj +1 more source