Results 61 to 70 of about 4,197,741 (336)
Primary depressives with secondary alcoholism compared with alcoholics and depressives
While a subset of depressed patients are believed to "self-medicate" their depression with alcohol, there are no studies comparing the phenomenological and diagnostic characteristics of patients with primary depression and secondary alcoholism with those of patients with depression or alcoholism alone.
E, Leibenluft +3 more
openaire +2 more sources
We present herein an unprecedented enantioselective isomerization of homoallylic and bishomoallylic secondary alcohols, catalyzed by a commercially available rhodium-complex and a base. This catalytic redox-neutral process provides an effective access to
Rui-Zhi Huang +4 more
semanticscholar +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Isohexide and sorbitol-derived, enzymatically synthesized renewable polyesters with enhanced Tg [PDF]
Sugar-based polyesters derived from sorbitol and isohexides were obtained via solvent-free enzymatic catalysis. Pendant hydroxyl groups, coming from the sorbitol units, were present along the polyester backbone, whereas the two isohexides, namely ...
Gustini, Liliane +4 more
core +2 more sources
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Biotransformation carried out by apples (Malus silvestris) resulted in enantiospecific hydrolysis of racemic acetates, the derivatives of secondary aromatic-aliphatic or terpenic alcohols. The alcohols are oxygenated to ketones (reversible reaction). The
Agnieszka Mironowicz
doaj +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
The conversion of ethoxylated fatty alcohols to the corresponding carboxylic acids through dehydrogenation/ oxidation using noble-metal catalysts has been studied.
Spiros Zlatanos +2 more
doaj +1 more source
Structural features and reactivity of (sparteine)PdCl_2: a model for selectivity in the oxidative kinetic resolution of secondary alcohols [PDF]
The chiral ligand (−)-sparteine and PdCl_2 catalyze the enantioselective oxidation of secondary alcohols to ketones and thus effect a kinetic resolution.
Stoltz, Brian M., Trend, Raissa M.
core +2 more sources
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source

