Results 61 to 70 of about 2,840,873 (295)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Syntheses of Enantiopure Aliphatic Secondary Alcohols and Acetates by Bioresolution with Lipase B from <em>Candida antarctica</em>

Molecules, 2012
The lipase B from <em>Candida antarctica</em> (Novozym 435^®, CALB) efficiently catalyzed the kinetic resolution of some aliphatic secondary alcohols: (±)-4-methylpentan-2-ol (<strong>1</strong>), (±)-5 ...
Richele P. Severino, Hercules V. Ferreira, André L. M. Porto, Lenilson C. Rocha   +3 more
doaj   +1 more source

Nickel-Catalyzed α‑Alkylation of Arylacetonitriles with Challenging Secondary Alcohols

, 2023
Nickel(II) complex 1 was utilized as a sustainable catalyst for α-alkylation of arylacetonitriles with challenging secondary alcohols. Arylacetonitriles with a wide range of functional groups were tolerated, and various cyclic and acyclic secondary ...
Amareshwar Nanda (14321942), Bidraha Bagh (2034982), Ratnakar Saha (9648251), Surajit Panda (8695056)   +3 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Effects of small amounts of pentadecan-2-one on the growth of Clostridium butyricum.

Journal of Lipid Research, 1978
Primary alcohols occur as trace lipids and are the only long-chain alcohol species present in Clostridium butyricum. Secondary alcohols do not occur physiologically in this microorganism.
J R Gilbertson, R A Gelman, T H Chiu, L I Gilbertson, T E Knauer   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

A Study of Amino Acid Metabolism and the Production of Higher Alcohols and Their Esters in Sparkling Wines

Fermentation
The presented article is focused on the study of amino acid metabolism and the related production of fusel alcohols and their esters in the secondary fermentation of sparkling wines.
Štěpán Tesařík, Mojmír Baroň, Kamil Prokeš, Denisa Macková   +3 more
doaj   +1 more source

Discovery and Redesign of a Family VIII Carboxylesterase with High (S)Selectivity toward Chiral sec-Alcohols

, 2022
Highly enantioselective lipase has been widely utilized in the preparation of versatile enantiopure chiral sec-alcohols through kinetic or dynamic kinetic resolution.
Seongsoon Park (3195249), Areum Park, Seongsoon Park, Areum Park (3195255)   +3 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Catalytic oxidation of secondary alcohols [PDF]

, 1992
The dioxygen oxidation of alcohols over platinum catalysts has been known for a long time. While of potential importance in synthetic procedures, this process has never found extensive use except in carbohydrate oxidations. Some reasons for this is the fact that this reaction only appears to work well in an aqueous medium in the presence of rather ...
Augustine, R. L., Doyle, L. K.
openaire   +5 more sources