Results 91 to 100 of about 4,144,121 (310)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Secondary flows and inlet skew in axial flow turbine cascades [PDF]
, 1987 This thesis presents a detailed experimental investigation of the effects of inlet skew on the secondary flows and losses in a linear cascade of high turning turbine rotor blades.
Walsh, J.A, Walsh, Joseph Anthony
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 2007 Reeder J. Algorithms for RNA secondary structure analysis : prediction of pseudoknots and the consensus shapes approach. Bielefeld (Germany): Bielefeld University; 2007.Our understanding of the role of RNA has undergone a major change in the last decade.
Reeder, Jens
core +1 more source
BeQuali – an archive in question
Revue d'anthropologie des connaissances, 2016 This paper addresses the difficulties generated by the archiving of data in social sciences and humanities through a case study: the set-up of a French qualitative archive, beQuali, whose first years (2006-2013) happened to be full of frictions.
Sophie Duchesne, Mathieu Brugidou
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Debt concentration and secondary market prices [PDF]
Using a model that distinguishes between large money center banks and smaller regional banks, this paper shows that the percentage of a country's debt held by the large banks affects the secondary market price of that country's debt: the higher the ...
Fernandez, Raquel, Ozler, Sule
core
Secondary transfer effects of intergroup contact via social identity complexity.
, 2014 Secondary transfer effects (STEs) of intergroup contact refer to the generalization of contact effects from a primary encountered outgroup to attitudes towards secondary outgroups (Pettigrew, 2009). Using two large, cross-sectional data sets from Germany
Hewstone, Miles +4 more
core +1 more source
Forum: Qualitative Social Research, 2005 Data bases or relational data base management systems (RDBMS) offer advantages over the common saving as data files for the storage of qualitative data in secondary analysis archives and larger research projects.
Heiner Legewie +5 more
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source