Results 81 to 90 of about 8,095,731 (348)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Secondary analysis of qualitative interview data (in Germany) – problems and open issues of a new research strategy

open access: yesJournal für Psychologie, 2007
Qualitative data are a rich and often not fully exploited source of research material. Nonetheless they are seldom reanalysed. The analysis of a nationwide German survey of qualitative researchers shows that there are some concerns and open issues ...
Irena Medjedovic
doaj  

Apories de la mise en banque : retour d’expérience sur la réutilisation d’enquêtes qualitatives

open access: yesTracés, 2019
Funding agencies and journal editors strongly incite researchers to share and archive their data, when they don’t compel them to do so. However, the ways we archive data have a strong influence on their potential for reuse.
Sophie Duchesne, Camille Noûs
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Detection of the secondary eclipse of Qatar-1b in the Ks band

open access: yes, 2016
Qatar-1b is a close-orbiting hot Jupiter ($R_p\simeq 1.18$ $R_J$, $M_p\simeq 1.33$ $M_J$) around a metal-rich K-dwarf, with orbital separation and period of 0.023 AU and 1.42 days.
Barrado, David   +6 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

BeQuali – an archive in question

open access: yesRevue d'anthropologie des connaissances, 2016
This paper addresses the difficulties generated by the archiving of data in social sciences and humanities through a case study: the set-up of a French qualitative archive, beQuali, whose first years (2006-2013) happened to be full of frictions.
Sophie Duchesne, Mathieu Brugidou
doaj   +1 more source

Packet Relaying Control in Sensing-based Spectrum Sharing Systems

open access: yes, 2013
Cognitive relaying has been introduced for opportunistic spectrum access systems by which a secondary node forwards primary packets whenever the primary link faces an outage condition.
Foukalas, F., Khattab, T., Poor, H. V.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Secondary Analysis of Database-Stored Qualitative Data: QUESSY as Interface Between QDA and RDBMS Systems

open access: yesForum: Qualitative Social Research, 2005
Data bases or relational data base management systems (RDBMS) offer advantages over the common saving as data files for the storage of qualitative data in secondary analysis archives and larger research projects.
Heiner Legewie   +5 more
doaj  

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