Results 61 to 70 of about 27,569,029 (304)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Geographical terms in English and Burmese arranged in alphabetical order : report of the Sub-Committee appointed by the Secondary Schools Board, at its meeeting held on the 25th June 1934.

, 1935
Electronic reproduction. Canberra, A.C.T.
Burma. Secondary School Board.
core  

Secondary Analysis of Database-Stored Qualitative Data: QUESSY as Interface Between QDA and RDBMS Systems

Forum: Qualitative Social Research, 2005
Data bases or relational data base management systems (RDBMS) offer advantages over the common saving as data files for the storage of qualitative data in secondary analysis archives and larger research projects.
Heiner Legewie, Nico de Abreu, Hans-Liudger Dienel, Dieter Münch, Thomas Muhr, Thomas Ringmayr   +5 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Can We Re-Use Qualitative Data Via Secondary Analysis? Notes on Some Terminological and Substantive Issues [PDF]

The potential gains and practical problems associated with secondary analysis of qualitative data have received increasing attention in recent years.
Martyn Hammersley
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Revisiting Classic Qualitative Studies

Forum: Qualitative Social Research, 2005
This paper explores methodological issues regarding the revisiting of "classic" qualitative studies. Classic studies pose particular issues for secondary analysis.
Mike Savage
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

BeQuali, une archive en question

Revue d'anthropologie des connaissances, 2016
This paper addresses the difficulties generated by the archiving of data in social sciences and humanities through a case study: the set-up of a French qualitative archive, beQuali, whose first years (2006-2013) happened to be full of frictions.
Sophie Duchesne, Mathieu Brugidou
doaj   +1 more source