Results 41 to 50 of about 27,569,029 (304)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Potentials and Limits of Secondary Analysis in a Specific Applied Context: The Case of EDF—Verbatim

Forum: Qualitative Social Research, 2005
In this paper we present the results of secondary analyses conducted on documents recorded in VERBATIM, the qualitative data archiving system and database developed by the Sociological Surveys Department (GRETS) of Electricité de France (EDF).
Magdalini Dargentas, Dominique Le Roux
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Reanalyzing Qualitative Interviews from Different Angles: The Risk of Decontextualization and Other Problems of Sharing Qualitative Data

Forum: Qualitative Social Research, 2005
In contrast to survey interviews, qualitative interviews are seldom reanalyzed. Besides obvious reasons such as ownership—and especially the culture of individualistic ownership—that impede reusing data, there is also methodological skepticism about ...
Harry Van den Berg
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Reality Lost? Re-Use of Qualitative Data in Classroom Video Studies

Forum: Qualitative Social Research, 2013
There has been debate on the re-use of qualitative data in the social sciences for more than a decade now. However, video data are rarely explicitly discussed in this regard, even though new media pose both new opportunities and new challenges when it ...
Emilia Andersson, Gard Ove Sørvik
doaj  

Rethinking resistance to ‘big IT’: a sociological study of why and when healthcare staff do not use nationally mandated information and communication technologies

Health Services and Delivery Research, 2014
Background: Nationally mandated information and communication technology (ICT) systems are often locally resented and little used.
Trisha Greenhalgh, Deborah Swinglehurst, Rob Stones   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

First-trimester SPISE mediates the association between early-pregnancy body fat percentage change and gestational diabetes mellitus: an exploratory secondary analysis of a prospective cohort

Frontiers in Endocrinology
BackgroundGestational diabetes mellitus (GDM) is closely related to maternal adiposity and insulin resistance. The rate of body fat percentage (BFP) change in early pregnancy may describe estimated BFP gain before routine glucose screening.
Xuran Zhang, Meiyuan Guo, Yingjie Chen
doaj   +1 more source

Informing the development of NICE (National Institute for Health and Care Excellence) quality standards through secondary analysis of qualitative narrative interviews on patients’ experiences

Health Services and Delivery Research, 2014
Background: We set out to explore if, and how, an archive of qualitative, narrative interviews covering over 60 health issues could be used to inform the development of National Institute for Health and Care Excellence (NICE) quality standards.
Sue Ziebland, Louise Locock, Ray Fitzpatrick, Tim Stokes, Glenn Robert, Norma O’Flynn, Kristina Bennert, Sara Ryan, Victoria Thomas, Angela Martin   +9 more
doaj   +1 more source