Results 41 to 50 of about 3,439,590 (350)
Egyptian Liver Journal, 2022 Background Viral hepatitis causes both liver inflammation and damage and is a serious health problem. Methods The indoor data of different types of hepatitis were collected from the official records of the administration of District Head Quarter Hospital
Muhammad Ashraf Khan
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Student Teachers' Perspectives on Academic Support Services in Open and Distance Learning
Journal of Research, Innovation, and Strategies for EducationAcademic support services are crucial for student success in open and distance learning (ODL), particularly in teacher education where learners balance multiple responsibilities.
Nawastheen Fareed Mohamed +4 more
doaj +1 more source
Meta-Analysis of Factors Associated with Occupational Therapist Burnout
Occupational Therapy International, 2021 Burnout, a reaction to chronic emotional stress, affects health and reduces the quality of service. Reportedly, healthcare professionals are especially vulnerable to burnout.
Eun-Young Park
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Developing STEM teacher leaders for urban contexts: accelerating STEM learning opportunities for Black and Brown youth [PDF]
School-University PartnershipsPurposeThis article discusses a Research-Practice Partnership (RPP) between an urban research university, two local school districts, and community-based science, technology, engineering, and mathematics (STEM) organizations designed to develop and ...
Christopher C. Jett, Natalie S. King
doaj +1 more source
The Egyptian Journal of Bronchology, 2022 Background Asthma and chronic obstructive pulmonary disease are the major airway diseases and are increasingly important causes of mortality, morbidity, and disability globally.
Muhammad Ashraf Khan
doaj +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
BMC Neurology, 2018 Background The evaluation of children with cerebral palsy (CP) focuses on activity level measurement to examine the effect of health-care interventions on their physical functioning in the home, school, and community settings.
Soojung Chae +2 more
doaj +1 more source