Results 81 to 90 of about 939,140 (300)

Investigating students’ conceptual difficulties on commutation relations and expectation value problems in quantum mechanics

SHS Web of Conferences, 2016
The aim of this study was to determine the students’ mathematical and conceptual challenges for two important concepts of quantum mechanics and also to investigate how the students make sense of their solutions with the conceptual basis. In this context,
Özcan Özgür
doaj   +1 more source

The evolution of the mood of the Izhevsk-Votkinsk workers in October 1917–December 1918 [PDF]

Омский научный вестник: Серия "Общество. История. Современность"
The article examines the problem of determining the views of Izhevsk-Votkinsk workers in 1917–1918, which led them to participate in the anti-Soviet uprising of 1918.
N. A. Zayats
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Teachers’ emotional appraisals and the reframing of student change in post-pandemic schools

Frontiers in Education
IntroductionThe return to “normal” schooling after the COVID-19 pandemic reactivated many of the emotional, instructional, and moral tensions teachers experienced during emergency remote teaching.
Rachel E. Gaines, Mei-Lin Chang, Melinda Palmer, Kristen C. Mosley   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Analysis of the Ugandan Experience on Teacher Job Satisfaction and Students’ Academic Performance at Uganda Certificate of Education in Secondary Schools in Western Uganda

, 2020
John Michael Edoru, Andrew Kasaija, A Latham, A Woods, Weasmer, M Shann, T Nyanga, P Mudhovozi, R Chireshe, L Maunganidze, J Saetang, K Sulumnad, P Thampitak, T Sungkaew, Johnson, Susan, Lieberman, Monahan, Frase Larry, A Latham, A Woods, Weasmer, S Dinham, C Scott, A Santhapparaj, S Alam, Odhiambo, F Noordin, Dinham Scott, Evans, Frase Larry, Johnson, Susan, Jonathan Darroux, Thibeti, A Latham, A Lieberman, M Malik, R Danish, J Munir, T Monahan, M Morris, Venkatesh, F Noordin, T Nyanga, P Mudhovozi, Chireshe, Maunganidze, G Odhiambo, O Oluseye, Amos, O Abiola, S Peng, Wright, B Rollins, D Thomas, I Saba, I Saba, Iqbal, Santhapparaj, Alam, Schultze, M Shann, A Woods, S Wood, M Zembylas, E Papanastasiou, S Zemmelman, Harvey, Heineman   +69 more
openalex   +1 more source

Recent developments in technical and vocational education in the Chinese senior secondary system [PDF]

, 1992
Tom Whiteside, Minxuan Zhang
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source