Results 51 to 60 of about 3,130,306 (355)

Experimental and numerical investigation of a pulsatile flow field in an S-shaped exhaust pipe of an automotive engine

open access: yesJournal of Fluid Science and Technology, 2017
A pulsatile turbulent flow within an S-shaped double bend pipe is experimentally and numerically studied to characterize the flow field in conditions resembling an automotive engine environment.
Junichi OKI   +7 more
doaj   +1 more source

Multi-Vortex Regulation for Efficient Fluid and Particle Manipulation in Ultra-Low Aspect Ratio Curved Microchannels

open access: yesMicromachines, 2021
Inertial microfluidics enables fluid and particle manipulation for biomedical and clinical applications. Herein, we developed a simple semicircular microchannel with an ultra-low aspect ratio to interrogate the unique formations of the helical vortex and
Shaofei Shen, Xin Wang, Yanbing Niu
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

NUMERICAL SIMULATION OF THE INFLUENCE OF A FILLET AND A BULB ON THE SECONDARY FLOW IN A COMPRESSOR CASCADE

open access: yesTASK Quarterly, 2002
Large fillet radii are typically found on highly loaded compressor rotors to ensure structural integrity. The objective of this paper is to investigate the impact of such real geometry effects on the flow at the hub section.
MARTIN HOEGER   +4 more
doaj  

Secondary Flow near an Undulatory Surface Induced by Wall Blocking Effect

open access: yesJournal of Fluid Science and Technology, 2007
Secondary mean motions of Prandtl's second kind near an undulatory surface are explained in terms of the turbulent blocking effect and kinematic boundary conditions at the surface, and the order of magnitude is estimated. The isotropic turbulence is
Kouji NAGATA   +2 more
doaj   +1 more source

Numerical Study of Multivortex Regulation in Curved Microchannels with Ultra-Low-Aspect-Ratio

open access: yesMicromachines, 2021
The field of inertial microfluidics has been significantly advanced in terms of application to fluid manipulation for biological analysis, materials synthesis, and chemical process control.
Shaofei Shen   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Influence of blade leading-edge form on the performance and internal flow pattern of a mixed-flow pump

open access: yesFrontiers in Energy Research, 2023
In this article, a typical mixed-flow pump was adopted as the research object to investigate the influence of the inlet structure within the impeller on the performance and internal flow patterns of the mixed-flow pump. First, three different blade inlet
Zhenggang Huo, Xiaoting Zha
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Numerical Analysis of Fluid Flow and Heat Transfer in Micro-Channel Heat Sinks with Double-Layered Complex Structure

open access: yesMicromachines, 2020
Micro-channel heat sink (MCHS) has been extensively used in various electronic cooling fields. Double-layered MCHS, or DL-MCHS, is regarded as one effective technique for high-heat-flux transfer and is expected to meet the ever-increasing heat load ...
Xiaogang Liu   +5 more
doaj   +1 more source

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