Results 71 to 80 of about 1,385,615 (259)
Dread and passion : primary and secondary teachers' views on teaching the arts [PDF]
, 2008 This article reports on a study of the views of Scottish teachers concerning the delivery of arts subjects within the 5-14 curriculum. Data were gathered through focus group interviews with primary, secondary and primary head teachers, and a ...
Raymond A.R. MacDonald +15 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Fluid flow induced by oscillating bodies and flows in cyclones [PDF]
, 1991 In this thesis the following aspects have been investigated: (i) the numerical solutions for unsteady 2-dimensional, incompressible viscous fluid flows induced by a harmonically oscillating cascade, and (ii) the fluid flows in industrial cyclones and ...
Yan, Baoshe
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Application of Hough transform for the identification of secondary flow patterns
, 2001 This paper reports the application of Hough transform image processing technique to identify the existence of secondary flow patterns in a curved channel.
Myers, D., Fung, C.C., Chung, K.P.
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Blade row interaction in radial turbomachines [PDF]
, 1999 A computational study has been performed to investigate the effects of blade row interaction on the performance of radial turbomachines, which was motivated by the need to improve our understanding of the blade row interaction phenomena for further ...
Sato, K., Sato, Kenji
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 1988 In the presen t work, a further numerical simulation of the starting flow around a flat plate normal to the direction of motion in a uniform fluid has been made by means of the discrete vortex method.
凌国灿, Bearman PW, Graham JWR
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