Results 71 to 80 of about 15,310,679 (339)
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Hebei University of Science and Technology, 2018 In order to enhance the heat transfer performance of CO2 heat pump, based on the numerical simulation method of Fluent, the law of supercritical CO2 cooling and heat transfer characteristics and secondary flow in the horizontal elliptical tube whose ...
Haiting CUI, Changle YI, Siwen LIU
doaj +1 more source
Axial and secondary flow study in a 90 deg bifurcation under pulsating conditions using PIV
, 2002 Both axial and secondary flow were experimentally studied in a 90-degree bifurcation of square tubes, under pulsating conditions and equal branch flow rates. The examined peak Reynolds number (Re) was in the range 330–830, and the Womersley parameter (α)
N. M. Nikolaidis +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Micromachines, 2020 Micro-channel heat sink (MCHS) has been extensively used in various electronic cooling fields. Double-layered MCHS, or DL-MCHS, is regarded as one effective technique for high-heat-flux transfer and is expected to meet the ever-increasing heat load ...
Xiaogang Liu +5 more
doaj +1 more source
The effect of end wall profiling on secondary flow in nozzle guide vanes [PDF]
, 1999 This thesis presents detailed investigations of the effect of end wall profiling on the secondary flow in a large scale, linear cascade with nozzle guide vanes.
Yan, Jin
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Heat Transfer and Flow Characteristics of Bidirectional Curved Wavy Microchannels
EnergiesCompared with straight microchannels, wavy microchannels have been shown to significantly improve the heat transfer capability of microchannel heat sinks.
Jiali Zhang, Guangyi Shao, Bo Wang
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source