Results 91 to 100 of about 1,385,615 (259)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Secondary Flow in Semi-Circular Ducts [PDF]

, 2020
Turbulent secondary flows are motions in the transverse plane, perpendicular to a main, axial flow. They are encountered in non-circular ducts and can, although the velocity is only of the order of 1-3% of the streamwise bulk velocity, affect the ...
G J Nathan, E M Lindmark, I A S Larsson, T S Lundström   +3 more
core  

Homogenization of initial cell distribution by secondary flow of medium improves cell culture efficiency. [PDF]

PLoS One, 2020
Fukuma Y, Inui T, Imashiro C, Kurashina Y, Takemura K.   +4 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Bend and orifice plate interactions and their influence on the pressure losses in internal flow systems

, 1980
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Experimental work has been carried out with a hydraulic flow test rig in which flows of water up to 65 kgs-l can be measured with a weigh-tank and its ...
Salvarli, Huseyin
core  

Flow of a blood analogue solution through microfabricated hyperbolic contractions

, 2011
The flow of a blood analogue solution past a microfabricated hyperbolic contraction followed by an abrupt expansion was investigated experimentally. The shape of the contraction was designed in order to impose a nearly constant strain rate to the fluid ...
Sousa, P.C., Pinho, I.S., Pinho, F.T., Oliveira, Monica, Alves, M.A.   +4 more
core   +1 more source

The evolution of secondary flow phenomena and their effect on primary shock conditions in shock tubes: Experimentation and numerical model. [PDF]

PLoS One, 2020
Kahali S, Townsend M, Mendez Nguyen M, Kim J, Alay E, Skotak M, Chandra N.   +6 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Theory of secondary flow in cascades

, 1978
1978-03-31It was in 1951 that Squire & Winter published a new conception that the secondary flow could occur in a bend through which a perfect fluid is flowing, as a result of a non-uniform distribution of velocity at entrance to the bend. Their idea was
Otsuka, Shintaro
core   +1 more source